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Table 1 Mean population parameters of antituberculosis drugs

From: Pharmacokinetics of antituberculosis drugs in critically ill patients with tuberculosis and acute respiratory failure

Parameter

RIF

INH

PZA

ka

0.459

3.58

1.41

CL/F

6.69

2.74

1.56

V/F

1 05

42.3

33.4

ωka

0.645

38.7

0.98

ωCL/F

0.391

65.6

0.23

ωV/F

0.469

46.8

0.38

ε

0.441

0.235

0.089