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Table 3 Clinical outcome of study patients

From: The effect of continuous versus intermittent renal replacement therapy on the outcome of critically ill patients with acute renal failure (CONVINT): a prospective randomized controlled trial

 

iHD group

CVVH group

P value

 

( n= 128)

( n= 122)

 

Survival at 14 days after RRT

39.5%

43.9%

0.81a

14-day mortality rate

43.6%

37.8%

0.63a

30-day mortality rate

52.4%

45.4%

0.60a

All-cause intrahospital mortality rate (last contact)

60.3%

54.6%

0.72a

Days until death

15.6 ± 44.5

18.5 ± 48.9

0.71

Days until death on ICU

15.5 ± 45.9

18.4 ± 50.0

0.73

Days until hospital discharge (in survivors)

51.2 ± 47.1

48.7 ± 49.7

0.78

Days in ICU

25.2 ± 40.1

22.3 ± 26.1

0.50

Days in hospital

33.9 ± 49.3

32.4 ± 37.4

0.79

Suspected reason for death (multiple possible)

Cardiac failure

31

22

0.42a

Pulmonary failure

39

31

0.59a

Sepsis

56

45

0.55a

CNS

7

6

0.92a

Hemorrhagy

5

4

0.93a

Withdrawal of therapy

4

2

0.74a

Days on RRT

17.2 ± 37.1

13.7 ± 17.9

0.35

Dialysis-free days

4.2 ± 9.6

3.1 ± 9.0

0.38

RRT switch (number of patients)

25 (19.5%)

56 (45.9%)

0.002a

Number of patients on RRT (% of survivors, days after ICU admission)

At 21 days

20 (32.3%)

20 (29.9%)

0.97a

At 60 days

14 (26.4%)

13 (22.8%)

0.90a

Serum creatinine at hospital discharge/last contact (in survivors; mg/dl)

2.18 ± 1.8

2.12 ± 1.7

0.85

Total days on vasopressors

4.3 ± 3.7

4.5 ± 3.7

0.75

Cumulative vasopressor dose (g)

Epinephrine

0.70

0.64

0.96

Norepinephrine

19.1

18.5

0.30

Dobutamine

150.2

137.9

0.56

Total days on mechanical ventilation

8.1 ± 8.8

7.2 ± 6.5

0.34

Total fluid balance (L)

20.5 ± 23.2

24.9 ± 28.4

0.19

  1. Between-group P values are given. Independent samples t test except a2). Means ± SD.