Range, units | Group | Day 1 | Day 3 | Day 5 | Day 7 | Day 10 | Day 15 | Day 21 | P value | |
---|---|---|---|---|---|---|---|---|---|---|
Day 1 (day 10) | ||||||||||
SOFA score | - | IHD | 13.3 | 13.0 | 11.5 | 10.1 | 7.6 | 8.3 | 5.8 | n.s. (n.s.) |
±3.7 | ±5.1 | ±4.6 | ±5.2 | ±5.0 | ±4.3 | ±0.8 | ||||
CVVH | 13.0 | 12.2 | 10.6 | 9.5 | 8.2 | 8.4 | 4.7 | |||
±4.0 | ±3.9 | ±4.2 | ±5.2 | ±5.1 | ±4.4 | ±7.2 | ||||
TISS-28 score | - | IHD | 45.3 | 42.0 | 41.2 | 37.8 | 29.9 | 35.8 | 37.6 | n.s. (n.s.) |
±9.5 | ±9.1 | ±9.7 | ±8.0 | ±9.0 | ±6.1 | ±5.5 | ||||
CVVH | 46.8 | 43.3 | 39.9 | 37.3 | 33.8 | 40.4 | 25.3 | |||
±10.2 | ±8.3 | ±9.1 | ±12.3 | ±10.8 | ±7.9 | ±17.2 | ||||
Serum creatinine | <1.20 mg/dl | IHD | 3.68 | 3.29 | 3.17 | 2.82 | 2.32 | 2.54 | 2.70 | n.s. (n.s.) |
±1.86 | ±2.59 | ±1.61 | ±1.51 | ±1.40 | ±1.40 | ±1.54 | ||||
CVVH | 3.74 | 2.18 | 2.31 | 2.08 | 1.93 | 1.85 | 1.86 | |||
±1.88 | ±1.19 | ±1.36 | ±1.40 | ±1.34 | ±1.42 | ±1.52 | ||||
Serum urea | 14-46 mg/dl | IHD | 164.8 | 121.5 | 125.4 | 124.9 | 105.9 | 120.4 | 117.6 | n.s. (n.s.) |
±83.4 | ±55.8 | ±50.0 | ±48.9 | ±53.9 | ±48.9 | ±60.4 | ||||
CVVH | 155.7 | 93.4 | 105.1 | 107.5 | 94.4 | 100.9 | 94.4 | |||
±70.0 | ±44.3 | ±53.2 | ±48.9 | ±48.3 | ±53.3 | ±65.7 | ||||
Urinary output (24 hours) | >500 ml | IHD | 922 | 944 | 914 | 1,331 | 1,714 | 1,376 | 3,570 | n.s. (n.s.) |
±1,299 | ±1,464 | ±1,415 | ±1,624 | ±1,338 | ±1,508 | ±3,614 | ||||
CVVH | 649 | 823 | 1,402 | 1,645 | 1,567 | 1,591 | 1,964 | |||
±948 | ±1,323 | ±1,785 | ±1,636 | ±1,474 | ±2,093 | ±757 | ||||
pH | 7.35-7.45 | IHD | 7.35 | 7.37 | 7.38 | 7.37 | 7.39 | 7.36 | 7.39 | n.s. (n.s.) |
±0.1 | ±0.1 | ±0.1 | ±0.1 | ±0.1 | ±0.1 | ±0.1 | ||||
CVVH | 7.36 | 7.37 | 7.40 | 7.38 | 7.37 | 7.39 | 7.39 | |||
±0.1 | ±0.1 | ±0.1 | ±0.2 | ±0.1 | ±0.1 | ±0.2 | ||||
Heart rate | 80-100 bpm | IHD | 104.0 | 93.8 | 90.9 | 92.9 | 86.9 | 85.5 | 86.5 | n.s. (n.s.) |
±26.1 | ±23.3 | ±20.3 | ±17.0 | ±16.4 | ±19.9 | ±12.9 | ||||
CVVH | 105.2 | 93.6 | 90.0 | 87.5 | 89.7 | 93.1 | 96.5 | |||
±21.3 | ±22.3 | ±20.4 | ±19.5 | ±18.1 | ±17.2 | ±15.4 | ||||
Mean arterial pressure | 50-80 mm Hg | IHD | 73.3 | 76.5 | 76.9 | 82.2 | 78.1 | 83.3 | 70.0 | n.s. (n.s.) |
±16.5 | ±17.6 | ±15.9 | ±16.7 | ±17.2 | ±11.9 | ±15.1 | ||||
CVVH | 72.0 | 76.2 | 76.6 | 77.7 | 81.2 | 75.5 | 75.3 | |||
±14.1 | ±13.8 | ±12.7 | ±12.4 | ±14.9 | ±25.9 | ±16.5 | ||||
Central venous pressure | 8-12 mm Hg | IHD | 14.7 | 12.9 | 12.2 | 12.2 | 11.1 | 10.7 | 12.9 | n.s. (n.s.) |
±5.3 | ±4.9 | ±3.9 | ±4.8 | ±3.9 | ±3.4 | ±2.94 | ||||
CVVH | 14.3 | 13.6 | 11.8 | 10.9 | 12.3 | 11.5 | 11.9 | |||
±5.4 | ±5.6 | ±4.2 | ±3.8 | ±4.6 | ±3.6 | 3.0 | ||||
Temperature | 36.5°C-37.5°C | IHD | 37.5 | 37.4 | 37.2 | 37.4 | 37.2 | 37.7 | 37.7 | n.s. (n.s.) |
±1.48 | ±1.03 | ±1.3 | ±0.65 | ±1.6 | ±0.67 | ±0.7 | ||||
CVVH | 37.5 | 37.1 | 37.1 | 37.1 | 37.2 | 37.1 | 37.7 | |||
±1.30 | ±1.16 | ±0.94 | ±0.90 | ±0.91 | ±1.05 | ±1.02 | ||||
C-reactive protein | <0.50 mg/dl | IHD | 18.0 | 15.6 | 10.5 | 10.5 | 8.3 | 7.14 | 11.7 | n.s. (n.s.) |
±10.0 | ±10.1 | ±8.3 | ±7.7 | ±6.7 | ±4.95 | ±8.25 | ||||
CVVH | 18.8 | 15.9 | 10.1 | 9.4 | 10.0 | 12.6 | 10.8 | |||
±10.3 | ±9.5 | ±8.55 | ±7.2 | ±7.1 | ±7.5 | ±7.6 |