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Table 3 Baseline clinical and laboratory characteristics by quartile of FT4

From: The impacts of thyroid function on the diagnostic accuracy of Cystatin C to detect acute kidney injury in ICU patients: a prospective, observational study

 

I

II

III

IV

P

Number

111

111

112

112

/

Age (years)

65.2 ± 16.7

69.4 ± 15.6

71.3 ± 15.1

70.3 ± 14.4

0.020

Men, Number (%)

65 (58.6)

67 (60.4)

72 (64.3)

56 (50.0)

0.171

APACHE-II score (points)

15.6 ± 7.3

15.1 ± 7.9

14.9 ± 6.7

16.3 ± 7.4

0.524

Baseline Scr (umol/L)

80.0 ± 45.9

80.0 ± 39.0

86.6 ± 46.4

84.0 ± 48.7

0.636

Current Scr (umol/L)

98.2 ± 89.4

100.7 ± 61.5

108.1 ± 79.7

106.8 ± 76.1

0.741

Cysc (mg/L)

1.23 ± 0.65

1.23 ± 0.51

1.32 ± 0.67

1.35 ± 0.79

0.354

Albumin (g/L)

32.7 ± 4.7

35.0 ± 6.1

35.1 ± 5.0

35.4 ± 5.5

0.000

TT3 (nmol/L)

0.83 ± 0.39

0.94 ± 0.34

0.89 ± 0.29

0.90 ± 0.36

0.109

TT4 (nmol/L)

72.04 ± 28.93

89.17 ± 23.00

90.03 ± 20.98

94.32 ± 24.29

0.000

FT3 (pmol/L)

3.04 ± 0.62

3.27 ± 0.54

3.42 ± 0.59

3.66 ± 0.92

0.000

FT4 (pmol/L)

11.93 ± 1.54

14.47 ± 0.53

16.14 ± 0.50

19.58 ± 3.17

0.000

TSH (IU/mL)

3.87 ± 16.16

1.26 ± 1.03

1.70 ± 1.84

1.14 ± 1.05

0.044

rT3 (nmol/L)

0.49 ± 0.21

0.54 ± 0.21

0.54 ± 0.24

0.57 ± 0.27

0.113

AKI (Number, %)

24 (21.6)

26 (23.4)

36 (32.1)

28 (25.0)

0.292

  1. Quartile cut points for FT4 were 13.49, 15.38 and 17.07 pmol/L, continuous variables were compared with one-way ANOVA, and dichotomous variables were compared with the chi-square test. ANOVA, analysis of variance; APACHE II score, Acute Physiology and Chronic Health Evaluation II score; Baseline Scr, baseline serum creatinine; Current Scr, serum creatinine on the entry to ICU; Cysc, Cystatin C; FT3, free triiodothyronine; FT4, free thyroxine; rT3, reverse triiodothyronine; TSH, thyroid-stimulating-hormone; TT3, total triiodothyronine; TT4, total thyroxine.