| Sham | Sham | Severe shock/RS | Severe shock/RL | Moderate shock/RS | Moderate shock/RL |
---|
Parameter
|
T = 20 minutes
|
T = 280 minutes
|
T = 170 minutes
|
T = 170 minutes
|
T = 230 minutes
|
T = 230 minutes
|
Hematocrit (%)
| 40.2 ± 0.24 | 32.01 ± 0.86 | 21.2 ± 0.7 | 21.3 ± 0.7 | 23.3 ± 1.2 | 23.8 ± 1.0 |
Na
+
(mmol/l)
| 138.8 ± 0.3 | 138.5 ± 0.5 | 141.1 ± 0.8 | 138.3 ± 0.9 | 140.7 ± 1.2 | 138.8 ± 0.8 |
Ca
2+
(mmol/l)
| 1.4 ± 0.01 | 1.4 ± 0.02 | 1.5 ± 0.03 | 1.5 ± 0.02 | 1.4 ± 0.04 | 1.4 ± 0.03 |
K
+
(mmol/l)
| 5.1 ± 0.05 | 5.5 ± 0.2 | 5.6 ± 0.1 | 5.6 ± 0.2 | 5.9 ± 0.3 | 5.6 ± 0.2 |
Cl
-
(mmol/l)
| 105 ± 0.6 | 111 ± 0.9 | 121 ± 0.6 | 117 ± 0.9*# | 122 ± 2.3 | 116 ± 1.5*# |
- Rats were subjected to moderate or severe hemorrhage and then resuscitated with either Ringer-saline (RS) or Ringer-lactate (RL). Electrolyte and hematocrit concentrations were measured before shock induction (baseline, T = 10 minutes), at the end of the experiment (sham group; shock/RS, shock/RL; T = 280 minutes) or at T = 150 minutes (that is, the last blood sample taken before the earliest death in the groups to be compared, shock/RS and shock/RL). The baseline values of the sham group were not significantly different from those of the other groups. Values are shown as the means ± SEM. *P <0.05 (vs. moderate shock/RS); # P <0.05 (vs. severe shock/RS).