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Table 2 Effects of Ringer-saline (RS) and Ringer-lactate (RL) on hematocrit and plasma electrolytes after shock

From: Volume replacement with Ringer-lactate is detrimental in severe hemorrhagic shock but protective in moderate hemorrhagic shock: studies in a rat model

 

Sham

Sham

Severe shock/RS

Severe shock/RL

Moderate shock/RS

Moderate shock/RL

Parameter

T = 20 minutes

T = 280 minutes

T = 170 minutes

T = 170 minutes

T = 230 minutes

T = 230 minutes

Hematocrit (%)

40.2 ± 0.24

32.01 ± 0.86

21.2 ± 0.7

21.3 ± 0.7

23.3 ± 1.2

23.8 ± 1.0

Na + (mmol/l)

138.8 ± 0.3

138.5 ± 0.5

141.1 ± 0.8

138.3 ± 0.9

140.7 ± 1.2

138.8 ± 0.8

Ca 2+ (mmol/l)

1.4 ± 0.01

1.4 ± 0.02

1.5 ± 0.03

1.5 ± 0.02

1.4 ± 0.04

1.4 ± 0.03

K + (mmol/l)

5.1 ± 0.05

5.5 ± 0.2

5.6 ± 0.1

5.6 ± 0.2

5.9 ± 0.3

5.6 ± 0.2

Cl - (mmol/l)

105 ± 0.6

111 ± 0.9

121 ± 0.6

117 ± 0.9*#

122 ± 2.3

116 ± 1.5*#

  1. Rats were subjected to moderate or severe hemorrhage and then resuscitated with either Ringer-saline (RS) or Ringer-lactate (RL). Electrolyte and hematocrit concentrations were measured before shock induction (baseline, T = 10 minutes), at the end of the experiment (sham group; shock/RS, shock/RL; T = 280 minutes) or at T = 150 minutes (that is, the last blood sample taken before the earliest death in the groups to be compared, shock/RS and shock/RL). The baseline values of the sham group were not significantly different from those of the other groups. Values are shown as the means ± SEM. *P <0.05 (vs. moderate shock/RS); # P <0.05 (vs. severe shock/RS).