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Table 2 Effects of Ringer-saline (RS) and Ringer-lactate (RL) on hematocrit and plasma electrolytes after shock

From: Volume replacement with Ringer-lactate is detrimental in severe hemorrhagic shock but protective in moderate hemorrhagic shock: studies in a rat model

  Sham Sham Severe shock/RS Severe shock/RL Moderate shock/RS Moderate shock/RL
Parameter T = 20 minutes T = 280 minutes T = 170 minutes T = 170 minutes T = 230 minutes T = 230 minutes
Hematocrit (%) 40.2 ± 0.24 32.01 ± 0.86 21.2 ± 0.7 21.3 ± 0.7 23.3 ± 1.2 23.8 ± 1.0
Na + (mmol/l) 138.8 ± 0.3 138.5 ± 0.5 141.1 ± 0.8 138.3 ± 0.9 140.7 ± 1.2 138.8 ± 0.8
Ca 2+ (mmol/l) 1.4 ± 0.01 1.4 ± 0.02 1.5 ± 0.03 1.5 ± 0.02 1.4 ± 0.04 1.4 ± 0.03
K + (mmol/l) 5.1 ± 0.05 5.5 ± 0.2 5.6 ± 0.1 5.6 ± 0.2 5.9 ± 0.3 5.6 ± 0.2
Cl - (mmol/l) 105 ± 0.6 111 ± 0.9 121 ± 0.6 117 ± 0.9*# 122 ± 2.3 116 ± 1.5*#
  1. Rats were subjected to moderate or severe hemorrhage and then resuscitated with either Ringer-saline (RS) or Ringer-lactate (RL). Electrolyte and hematocrit concentrations were measured before shock induction (baseline, T = 10 minutes), at the end of the experiment (sham group; shock/RS, shock/RL; T = 280 minutes) or at T = 150 minutes (that is, the last blood sample taken before the earliest death in the groups to be compared, shock/RS and shock/RL). The baseline values of the sham group were not significantly different from those of the other groups. Values are shown as the means ± SEM. *P <0.05 (vs. moderate shock/RS); # P <0.05 (vs. severe shock/RS).