Control | Metabolic acidosis | Respiratory acidosis | |||||||
---|---|---|---|---|---|---|---|---|---|
Baselinest | Baselineend | Δ | Baseline | Acidosis | Δ | Baseline | Acidosis | Δ | |
HR | 101 ± 20 | 119 ± 39 | 93 ± 12 | 161 ± 56 | ↑ | 99 ± 25 | 200 ± 42 | ↑ | |
SV | 44.8 ± 8.7 | 44.2 ± 18.4 | 51.6 ± 11.9 | 34.1 ± 13.4 | ↓ | 48.2 ± 17.4 | 35.2 ± 8.4 | ↓ | |
GEDV | 660.4 ± 116.2 | 691.1 ± 123.6 | 620.3 ± 136.6 | 571.8 ± 125.1 | 709.1 ± 152.9 | 693.7 ± 113.6 | |||
CO | 4.5 ± 0.8 | 4.8 ± 1.2 | 4.8 ± 1.1 | 5.3 ± 2.0 | 4.5 ± 1.1 | 7.3 ± 1.8 | ↑ | ||
MAP | 94.5 ± 15.6 | 97.3 ± 16.9 | 87.4 ± 15.3 | 99.7 ± 18.4 | 88.7 ± 5.6 | 105.6 ± 9.4 | ↑ | ||
CVP | 11.1 ± 2.1 | 10.6 ± 2.6 | 9.0 ± 2.6 | 9.3 ± 2.4 | 12.1 ± 3.8 | 12.1 ± 1.1 | |||
MPAP | 25.1 ± 5.2 | 26.1 ± 3.9 | 23.1 ± 3.1 | 42.9 ± 8.4 | ↑ | 24.4 ± 1.7 | 40.3 ± 6.7 | ↑ | |
PCWP | 9.5 ± 1.9 | 9.3 ± 2.4 | 7.9 ± 2.5 | 9.3 ± 2.7 | 10.9 ± 1.2 | 9.3 ± 2.4 | |||
SVR | 1,539 ± 409 | 1,520 ± 489 | 1,350 ± 327 | 1,564 ± 729 | 1,412 ± 327 | 1,068 ± 209 | ↓ | ||
PVR | 287 ± 71 | 301 ± 142 | 268 ± 92 | 591 ± 283 | ↑ | 259 ± 60 | 356 ± 116 | ↑ | |
ITBV | 825.5 ± 145.3 | 863.9 ± 154.5 | 796 ± 173.3 | 715.9 ± 168.9 | ↓ | 886.4 ± 191.1 | 867.1 ± 142 | ||
LVSW | 59.5 ± 17.2 | 52.8 ± 20 | 61.8 ± 17.9 | 45.6 ± 18 | 58.4 ± 24.9 | 55.4 ± 12.4 | |||
LVSWtot | 6,056 ± 1,606 | 6,183 ± 1,783 | 5,784 ± 1,924 | 7,179 ± 2,835 | 5,788 ± 1,368 | 11,124 ± 2,968 | ↑ | ||
RVSW | 15.5 ± 4.5 | 13.7 ± 4.5 | 16.3 ± 5.6 | 20.4 ± 10.8 | 16.7 ± 7.9 | 21.1 ± 7.3 | |||
RVSWtot | 1,606 ± 541 | 1,618 ± 419 | 1,492 ± 420 | 3,088 ± 1,414 | ↑ | 1,650 ± 539 | 4,166 ± 1,313 | ↑ | |
HVSW | 7,662 ± 2,041 | 7,801 ± 2,146 | 7,276 ± 2,201 | 10,267 ± 4,086 | 7,438 ± 1,874 | 15,290 ± 4,135 | ↑ | ||
Hearte | 417.6 ± 111.2 | 425.2 ± 117 | 396.6 ± 120 | 559.6 ± 222.7 | 405.4 ± 102.1 | 833.4 ± 225.4 | ↑ |