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Figure 4 | Critical Care

Figure 4

From: Effects of clinically relevant acute hypercapnic and metabolic acidosis on the cardiovascular system: an experimental porcine study

Figure 4

Effects of acidosis on ventricular action potential. Empty columns, control Tyrode solution. Solid columns, acidic solution (Tyrode solution with a pH of 7.1). (A) Effects of acidic solution on action potential in trabeculae from control pigs (cycle length of 500, 1,000, and 2,000 ms). Left panel, pooled data, APD90. Right panel, representative action potentials at stimulation frequency of 1 Hz in control and acidic solutions. (B) Effects of acidic solution on action potential in trabeculae from pigs with MAC (cycle length of 500, 1,000, and 2,000 ms). Left panel, pooled data, APD90. Right panel, representative action potentials at stimulation frequency of 1 Hz in control and acidic solutions. (C) Effects of acidic solution on action potential in trabeculae from pigs with HCA (cycle length of 500, 1,000, and 2,000 ms). Left panel, pooled data, APD90. Right panel, representative action potentials at stimulation frequency of 1 Hz in control and acidic solutions.

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Critical Care

ISSN: 1364-8535