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Table 1 The scoring system for disseminated intravascular coagulation (DIC) as established by the Japanese Association for Acute Medicine (JAAM) and International Society on Thrombosis and Haemostasis (ISTH)

From: A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis

A. JAAM DIC scoring system

 

Score

Systemic inflammatory response syndrome criteria

 ≥3

1

 0-2

0

Platelet counts (109/L)

 <80, or a more than 50% decrease within 24 hours

3

 ≥80, <120 or a more than 30% decrease within 24 hours

1

 ≥120

0

Prothrombin time (value of patient/normal value)

 ≥1.2

1

 <1.2

0

Fibrin/fibrinogen degradation products (FDP) (mg/L)

 ≥25

3

 ≥10 <25

1

 <10

0

Diagnosis

 4 points or more

DIC

B. ISTH overt DIC scoring system

 

Score

Platelet counts (109/L)

 

 <50

2

 ≥50 <100

1

 ≥100

0

Elevated fibrin-related marker

(for example soluble fibrin monomers/fibrin degradation products)

 Strong increase

3

 Moderate increase

2

 No increase

0

Prolonged prothrombin time (sec)

 ≥6

2

 ≥3 <6

1

 <3

0

Fibrinogen level (g/mL)

 <100

1

 ≥100

0

If >5: compatible with overt DIC; repeat scoring daily

If <5: suggestive (not affirmative) for non-overt DIC; repeat next 1-2 days