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Table 1 Influx of neutrophils in bronchiolar lavage fluid of control or anti-HMGB1-treated mice

From: High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia

Time point (t)

Control IgG2b

Anti-HMGB1

t = 6 h

508 (390 to 1169)

520 (207 to 736)

t = 24 h

434 (391 to 580)

665 (450 to 934)

t = 48 h

1376(1054 to 1796)

1339 (1147 to 1770)

t = 72 h

600 (516 to 891)

519(425 to 841)

  1. Neutrophil numbers (×1,000/ml) in BAL fluid at 6, 24, 48 and 72 hours after intranasal S. aureus infection in control and anti-HMGB1-treated mice. Data are medians (interquartile ranges); n = 7 to 8 mice per group per time point. HMGB1, High mobility group box 1.
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Critical Care

ISSN: 1364-8535