Data available | Progression of AKI | Data available | No progression of AKI | P-value | |
---|---|---|---|---|---|
N = 153 | N = 270 | ||||
Age, years | 153 | 64.0 (51.0 to 78.0) | 270 | 63.0 (52.0 to 73.0) | 0.1 |
Gender, male | 153 | 92 (60.1) | 270 | 184 (68.1) | 0.1 |
Baseline creatinine available | 153 | 108 (70.6) | 270 | 184 (68.1) | 0.6 |
Comorbidity | |||||
Hypertension | 153 | 81 (52.9) | 270 | 126 (46.7) | 0.22 |
Systolic heart failure or arteriosclerosis | 153 | 30 (19.6) | 270 | 45 (16.7) | 0.45 |
COPD | 153 | 15 (9.8) | 270 | 38 (14.1) | 0.2 |
Chronic kidney disease | 153 | 17 (11.1) | 270 | 7 (2.6) | <0.001 |
Chronic liver disease | 153 | 8 (5.2) | 270 | 12 (4.4) | 0.72 |
Diabetes mellitus | 153 | 42 (27.5) | 270 | 50 (18.5) | 0.032 |
Hypotension prior to ICU | 151 | 64 (42.4) | 267 | 75 (28.1) | 0.003 |
Hypovolemia prior to ICU | 151 | 78 (51.7) | 268 | 96 (35.8) | 0.002 |
Radiocontrast dye prior to ICU | 153 | 44 (28.8) | 268 | 52 (19.4) | 0.03 |
Emergency admission | 153 | 148 (96.7) | 270 | 267 (98.9) | 0.12 |
Operative admission | 153 | 49 (32.0) | 270 | 59 (21.9) | 0.02 |
Community acquired infection | 152 | 76 (50.0) | 270 | 137 (50.7) | 0.88 |
Source of infection | |||||
Pulmonary | 139 | 70 (50.4) | 246 | 155 (63.0) | 0.02 |
Abdominal | 139 | 45 (32.4) | 246 | 52 (21.1) | 0.02 |
Genitourinary | 139 | 14 (10.1) | 246 | 12 (4.9) | 0.05 |
Soft tissue | 139 | 14 (10.1) | 246 | 28 (12.4) | 0.7 |
SAPS II points | 153 | 43.0 (35.0 to 55.0) | 270 | 38.0 (30.0 to 46.0) | <0.001 |
SAPS II points without age and renal components | 153 | 24.0 (18.0 to 30.0) | 270 | 24.0 (17.0 to 31.0) | 0.7 |
SOFA D1 points | 153 | 9.0 (7.0 to 11.0) | 270 | 7.0 (5.0 to 9.0) | <0.001 |
SOFA D1 points, without renal points | 153 | 8.0 (6.0 to 10.0) | 270 | 7.0 (5.0 to 9.0) | 0.001 |
During ICU stay | |||||
Mechanical ventilation | 153 | 117 (76.5) | 270 | 168 (62.2) | 0.003 |
Use of sepsis corticosteroids | 151 | 55 (36.4) | 264 | 46 (17.4) | <0.001 |
Any vasoactive treatment | 153 | 134 (87.6) | 270 | 181 (67.0) | <0.001 |
Furosemide | 153 | 131 (85.6) | 270 | 189 (70.0) | <0.001 |
Dose of furosemide (iv) per ICU day, mg/day | 153 | 13.6 (3.5-33.9) | 270 | 4.2 (0.0-16.0) | <0.001 |
Aminoglycoside antibiotics | 153 | 1 (0.7) | 270 | 6 (2.2) | 0.22 |
Peptidoglycan antibiotics | 153 | 16 (10.5) | 270 | 29 (10.7) | 0.93 |
ACE inhibitor or ARB | 153 | 10 (6.5) | 270 | 26 (9.6) | 0.27 |
NSAID | 153 | 5 (3.3) | 270 | 17 (6.3) | 0.18 |
Radiocontrast dye | 153 | 15 (9.8) | 270 | 33 (12.2) | 0.45 |
Length of stay | |||||
ICU | 153 | 5.7 (3.3 to 10.3) | 270 | 3.8 (2.0 to 7.0) | <0.001 |
Hospital | 153 | 16.0 (9.5 to 26.5) | 270 | 15.0 (9.0 to 23.8) | 034 |
90-day mortality | 153 | 50 (32.7) | 270 | 51 (18.9) | 0.001 |