Decreased HLA-DR antigen-associated invariant chain (CD74) mRNA expression predicts mortality after septic shock

Table 3 Correlations

	HLA-DMB	HLA-DMA	CD74	CIITA	HLA-DRA
mHLA-DR	0.52	0.51	0.54	0.49	0.53
*HLA-DMB*		0.88	0.89	0.85	0.92
*HLA-DMA*			0.87	0.87	0.92
*CD74*				0.88	0.87
*CIITA*					0.87

Major histocompatibility class II-related genes mRNA levels and circulating monocyte HLA-DR expression (mHLA-DR) were measured in blood samples obtained from 93 septic shock patients at Day 3 or Day 4 after the onset of shock. Correlation coefficients are shown (Spearman’s rank correlation test). CD74, HLA-DR antigen-associated invariant chain; CIITA, class II transactivator; HLA-DR/DM, human leukocyte antigen-DR/DM.

ISSN: 1364-8535