Skip to main content

Table 2 Demographic and clinical data for septic shock patients

From: Decreased HLA-DR antigen-associated invariant chain (CD74) mRNA expression predicts mortality after septic shock

 

Survivors n = 66 (%)

Non-survivors n = 27 (%)

P-value

Total n = 93 (%)

Male

44 (67)

16 (59)

ns

60 (65)

Age*

61 [53 to 73]

65 [55 to 77]

ns

62 [54 to 75]

SAPS II on admission*

45 [34 to 54]

57 [46 to 69]

<0.0001

48 [35 to 60]

Duration length in ICU*

25 [8 to 37]

12 [5-17]

0.0074

21 [6 to 31]

SOFA*

9 [7-11]

12 [9-12]

0.0013

10 [8-12]

Co-morbidities

  

<0.001

 

   0

44 (65.7)

4 (15.4)

 

48 (51.61)

   1

19 (28.4)

16 (61.5)

 

35 (37.6)

   >2

4 (5.9)

6 (23.1)

 

10 (10.8)

Type of admission

  

ns

 

   Surgery

30 (46)

10 (37)

 

40 (43)

   Medical

36 (54)

17 (63)

 

53 (57)

Type of infection

  

ns

 

   Community acquired

32 (49)

18 (67)

 

50 (54)

   Nosocomial

34 (51)

9 (33)

 

43 (46)

Suspected infection

  

ns

 

   Clinically documented

9 (14)

3 (11)

 

12 (13)

   Microbiologically

55 (83)

22 (85)

 

78 (84)

   Documented

    

    -Bacilli Gram (−)

35 (53)

12 (44)

 

47 (51)

    -Cocci Gram (+)

23 (35)

11 (41)

 

34 (37)

    -Fungi

14 (21)

8 (30)

 

22 (23)

Primary site of infection

  

0.0015

 

    -Abdominal

23 (35)

8 (30)

 

31 (33)

    -Pulmonary

27 (41)

15 (55)

 

42 (43)

    -Other

0 (0)

4 (15)

 

4 (4)

  1. Blood samples were obtained from 93 septic shock patients at Day 3 or Day 4 after the onset of shock. Categorical data are presented as number of cases and percentages respective to the corresponding patient’s population between brackets. Continuous data (*) are presented as medians and interquartile ranges [Q1 to Q3]. SAPS II, Simplified Acute Physiologic Score II calculated at inclusion in the protocol; SOFA score, Sequential Organ Failure Assessment score measured after 24 h of ICU stay. Comparisons between groups (survivors vs non-survivors) were made using the non-parametric Mann Whitney U-test for continuous variables and the Pearson chi-squared test, as appropriate, for categorical data. Most frequent co-morbidities included chronic respiratory failure (n = 10 non-survivors and 4 survivors), chronic cardiac failure (n = 3 non-survivors and 4 survivors), chronic renal failure (n = 3 non-survivors and 5 survivors) and metastatic cancer (n = 3 non-survivors and 5 survivors). Other co-morbidities included hematologic malignancies, type II diabetes and chronic hepatic failure.
Back to article page

Critical Care

ISSN: 1364-8535