Figure 1

MHC class II related genes and protein expressions in survivors and non-survivors after septic shock. Circulating monocyte HLA-DR expression mHLA-DR – number of antibodies bound per cell (AB/C) was measured by flow cytometry and major histocompatibility class II related genes mRNA levels were evaluated by qRT-PCR in blood samples obtained from 93 septic shock patients at Day 3 or Day 4 after the onset of shock. Results are presented as box-plots as well as individual values in survivors (n = 66) and non-survivors (n = 27). Mann Whitney U-test was used to compare results between groups. CD74, HLA-DR antigen-associated invariant chain, CIITA, class II transactivator; HLA-DR/DM, human leukocyte antigen-DR/DM.