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Table 3 HLA-DR expression (antibody/cell) on peripheral blood monocytes and AMs

From: Dysfunction of alveolar macrophages after cardiac surgery and postoperative pneumonia? - an observational study

 

Peripheral blood monocytes

AMs

Time point

Preoperative

Postoperative

p

Preoperative

Postoperative

P

All (n = 31)

26,587 (20,410, 31,478)

13,996 (11,724, 17,706)

0.001a

985,234 (698,683, 1,293,531)

712,564 (320,726, 941,120)

0.001a

Group 1 (n = 28)

26,266 (20,646, 31,415)

15,258 (12,365, 18,580)

0.001a

1,009,337 (739,280, 1,294,545)

736,306 (430,604, 943,491)

0.002a

Group 2 (n = 3)

27,882 (12,325, 34,088)

10,292 (10,288, 13,389)

n/a

652,262 (505,628, 985,234)

106,139 (42,434, 417,111)

n/a

  1. HLA-DR expression on peripheral blood monocytes as well as on AMs was significantly reduced after surgery. In group 2 a strong reduction without statistical significance was seen. Data are given as medians and IQR in brackets. The Wilcoxon test was used to calculate significant difference for the depending variables; astatistically significant difference. HLA-DR, human leukocyte antigen-DR; AM, alveolar macrophage.