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Table 2 Differential subsets of peripheral blood and bronchoalveolar lavage samples

From: Dysfunction of alveolar macrophages after cardiac surgery and postoperative pneumonia? - an observational study

  Peripheral blood subsets (%) Bronchoalveolar subsets (%)
Time point Preoperative Postoperative P Preoperative Postoperative P
Macrophages (n = 33) n/a n/a   63.5 (38.8, 76.5) 52.2 (21.5, 69.6) 0.018a
Group 1 (n = 30) n/a n/a   63.2 (35.2, 73.0) 53.4 (22.0, 70.2) 0.06
Group 2 (n = 3) n/a n/a   77.1 (56.7, 85.7) 27.9 (7.5, 57.4) n/a
Monocytes (n = 33) 8.0 (6.7, 9.9) 4.0 (2.6, 5.7) 0.001a 3.4 (2.3, 4.6) 3.1 (1.8, 4.7) 0.83
Group 1 (n = 30) 7.9 (6.7, 10.2) 4.4 (2.8, 6.0) 0.001a 3.3 (2.3, 4.2) 3.2 (2.0, 4.7) 0.758
Group 2 (n = 3) 9.3 (7.1, 9.6) 2.3 (2.2, 4.0) n/a 4.3 (2.4, 11.9) 1.8 (1.7, 7.5) n/a
Lymphocytes (n = 33) 21.4 (17.1, 30.3) 7.4 (5.8, 11.9) 0.001a 11.4 (7.4, 14.5) 9.2 (4.6, 17.1) 0.99
Group 1 (n = 30) 21.6 (17.5, 29.7) 7.5 (5.7, 11.7) 0.001a 11.5 (7.7, 15.7) 9.9 (5.7, 19.2) 0.673
Group 2 (n = 3) 6.4 (5.8, 34.4) 6.9 (6.2, 10.2) n/a 13.1 (4.7, 14.2) 4.3 (3.4, 11.4) n/a
Neutrophils (n = 33) 66.7 (57.7, 74.3) 87.4 (81.4, 91.2) 0.001a 10.6 (3.1, 28.8) 15.1 (2.1, 46.7) 0.088
Group 1 (n = 30) 66.6 (57.8, 74.0) 87.2 (80.4, 91.3) 0.001a 11.3 (3.1, 35.5) 14.3 (1.8, 41.0) 0.254
Group 2 (n = 3) 82.4 (56.6, 83.5) 88.9 (87.4, 91.3) n/a 4.8 (3.1, 11.7) 45.2 (15.1, 82.7) n/a
  1. In the peripheral blood samples (n = 33) the monocytes and lymphocytes were significantly reduced after surgery, whereas the neutrophils were significantly elevated. The findings in the bronchiolar lavage samples (n = 33) were different. The trend was similar to the blood samples but only the percentage of macrophages was significantly reduced after surgery. Data are given as medians and IQR in brackets. The Wilcoxon test was used to calculate significant difference for the dependent variables; asignificantly different; n/a, not available.