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Figure 5 | Critical Care

Figure 5

From: The role of intestinal mucosa injury induced by intra-abdominal hypertension in the development of abdominal compartment syndrome and multiple organ dysfunction syndrome

Figure 5

Pathological changes of intestinal mucosa observed by transmission electron microscopy. (A) Mitochondria (M) and microvilli (mV) in a normal jejunal mucosal epithelial cell (×10,000); (B) mildly swollen mitochondria but intact microvilli can be seen after an intra-abdominal pressure (IAP) of 15 mmHg for 4 hrs (×14,000); (C and D) severe mitochondrial swelling (M) and disruption of the cristae, and shortened, irregular and vacuolated microvilli can be seen after an IAP of 25 mmHg for 2 hrs (C: ×14,000, D: ×17,000); (E and F) discontinuous cell tight junctions, mitochondrial ballooning, degeneration and necrosis, and vacuolated and necrotic microvilli were seen that had begun to flake from the surface of membrane after an IAP of 25 mmHg for 6 hrs (E: ×20,000, F: ×7,000).

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Critical Care

ISSN: 1364-8535