Figure 4From: The role of intestinal mucosa injury induced by intra-abdominal hypertension in the development of abdominal compartment syndrome and multiple organ dysfunction syndromePathological changes of intestinal mucosa observed by light microscopy. (A) Normal control; (B) after an intra-abdominal pressure (IAP) of 15 mmHg for 4 hrs, jejunal villi were moderately edematous, mild neutrophil infiltration can be seen, but gross integrity was relatively maintained; (C) after an IAP of 25 mmHg for 2 hrs, obvious neutrophil infiltration and central lacteal expansion were seen, along with thickening of the walls of the villi; (D) after an IAP of 25 mmHg for 4 hrs, extensive jejunal villi erosion and necrosis were seen. (Magnification for each: ×100).Back to article page