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Table 2 Cox proportional hazards analyses for 28-day and 90-day mortality according to baseline RDW value and ΔRDW 72hr-adm

From: An increase in red blood cell distribution width from baseline predicts mortality in patients with severe sepsis or septic shock

Groups based on baseline RDW value and ΔRDW72hr-adm Unadjusted model Adjusted model 1 Adjusted model 2
  HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
28-day mortality
 Group 1 1.0 - 1.0 - 1.0 -
 Group 2 10.09 (2.24 to 45.52) 0.003 4.57 (0.93 to 22.47) 0.062 4.86 (0.93 to 25.29) 0.060
 Group 3 3.64 (0.77 to 17.14) 0.102 1.31 (0.26 to 6.49) 0.743 1.72 (0.34 to 8.69) 0.513
 Group 4 21.78 (4.85 to 96.95) <0.001 7.85 (1.63 to 37.76) 0.010 9.97 (1.99 to 49.91) 0.005
90-day mortality
 Group 1 1.0 - 1.0 - 1.0 -
 Group 2 12.41 (2.80 to 54.98) 0.001 4.93 (1.06 to 22.94) 0.042 4.72 (1.00 to 22.27) 0.050
 Group 3 7.44 (1.71 to 32.34) 0.007 3.85 (0.87 to 17.04) 0.076 4.78 (1.07 to 21.31) 0.040
 Group 4 33.41 (7.71 to 144.70) <0.001 11.66 (2.57 to 52.97) 0.001 13.74 (2.95 to 64.10) 0.001
  1. Unadjusted Model: crude relative risk. Adjusted Model 1: adjusted for age, sex, SOFA score, Charlson Comorbidity Index, renal replacement therapy, albumin, hemoglobin, lactate, and C-reactive protein. Adjusted Model 2: Model 1 plus adjustment for infection site. RDW, red cell distribution width.