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Table 3 B cells (B220 high ) gained BTLA expression (MFI) 72 hours following CLP surgery

From: B and T lymphocyte attenuator expression on CD4+ T-cells associates with sepsis and subsequent infections in ICU patients

  Sham mice (n = 6) CLP mice (n = 10) P value
Blood – 24 hours post surgery    
 % BTLA+ (SEM) 99.98 (0.02) 98.88 (0.25) <0.01
 BTLA MFI (SEM) 43.74 (1.74) 37.92 (3.80) 0.24
Blood – 72 hours post surgery    
 % BTLA+ (SEM) 99.92 (0.02) 98.94 (0.66) 0.31
 BTLA MFI (SEM) 48.54 (1.13) 71.15 (2.66) <0.01
Spleen – 24 hours post surgery    
 % BTLA+ (SEM) 99.83 (0.03) 99.85 (0.02) 0.65
 BTLA MFI (SEM) 31.91 (0.60) 33.96 (1.10) 0.16
Spleen – 72 hours post surgery    
 % BTLA+ (SEM) 99.88 (0.02) 99.86 (0.05) 0.77
 BTLA MFI (SEM) 26.33 (2.08) 37.89 (1.76) <0.01
  1. P value evaluated via an unpaired, two-tailed Student’s t test ± standard error of the mean (SEM); bold values are significant. Mean fluorescent intensity (MFI) experiments were conducted with three to five mice for each group and then repeated for confirmation of the results. BTLA, B and T lymphocyte attenuator; CLP, cecal ligation and puncture.