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Table 3 B cells (B220 high ) gained BTLA expression (MFI) 72 hours following CLP surgery

From: B and T lymphocyte attenuator expression on CD4+ T-cells associates with sepsis and subsequent infections in ICU patients

 

Sham mice (n = 6)

CLP mice (n = 10)

P value

Blood – 24 hours post surgery

   

 % BTLA+ (SEM)

99.98 (0.02)

98.88 (0.25)

<0.01

 BTLA MFI (SEM)

43.74 (1.74)

37.92 (3.80)

0.24

Blood – 72 hours post surgery

   

 % BTLA+ (SEM)

99.92 (0.02)

98.94 (0.66)

0.31

 BTLA MFI (SEM)

48.54 (1.13)

71.15 (2.66)

<0.01

Spleen – 24 hours post surgery

   

 % BTLA+ (SEM)

99.83 (0.03)

99.85 (0.02)

0.65

 BTLA MFI (SEM)

31.91 (0.60)

33.96 (1.10)

0.16

Spleen – 72 hours post surgery

   

 % BTLA+ (SEM)

99.88 (0.02)

99.86 (0.05)

0.77

 BTLA MFI (SEM)

26.33 (2.08)

37.89 (1.76)

<0.01

  1. P value evaluated via an unpaired, two-tailed Student’s t test ± standard error of the mean (SEM); bold values are significant. Mean fluorescent intensity (MFI) experiments were conducted with three to five mice for each group and then repeated for confirmation of the results. BTLA, B and T lymphocyte attenuator; CLP, cecal ligation and puncture.