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Table 3 Comparison of biological parameters between survivors and non survivors (ICU mortality) of the septic shock cohort (n = 72)

From: The prognostic value of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) deficiency in septic shock patients involves interleukin-6 and is not dependent on disseminated intravascular coagulation

 

Survivors

Non-survivors

P-value

(n = 43)

(n = 29)

Disseminated intravascular coagulation (DIC)

10/43 (23%)

9/29 (31%)

0.59

ISTH score

3 (1, 4)

4 (2, 5)

0.67

Platelet count, G/l

65 (20, 184)

87 (47, 195)

0.30

ADAMTS13 activity <30%

17/43 (37%)

19/29 (66%)

0.05

ADAMTS13 activity <5%

1/43

3/29

-

ADAMTS13:Ag, ng/mL

483 (384, 613)

491 (418, 696)

0.24

VWF:Ag, %

477 (341, 656)

560 (478, 835)

0.05

IL-6, pg/mL

107 (48, 418)

840 (204, 1089)

0.03

  1. Values are expressed as median and interquartile range for continuous variables and as number and proportion for categorical variables. Continuous variables were compared using the non-parametric Mann–Whitney U-test. Categorical variables were compared using the χ2 test. P <0.05 was considered significant. ISTH, International Society for Thrombosis and Haemostasis; ADAMTS13, a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13; ADAMTS13:Ag, ADAMTS13 antigen; VWF:Ag, von Willebrand Factor antigen.