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Table 1 Baseline characteristics

From: Association between haptoglobin, hemopexin and mortality in adults with sepsis

Characteristic Overall Survivors Non-survivors P-value
  n = 387 n = 303 (78.2%) n = 84 (21.8%)  
Age, years 57 (48, 68) 56 (47, 67) 61 (54, 70) 0.012
Men, n (%) 216 (55.8%) 164 (54.1%) 52 (61.9%) 0.217
APACHE II on enrollment 28 (22, 33) 26 (21, 32) 31 (26, 36) <0.001
On dialysis at enrollment, n (%) 14 (3.6%) 13 (4.3%) 1 (1.2%) 0.319
PRBC transfusion, n (%) 90 (23.3%) 65 (21.5%) 25 (29.8%) 0.144
Chronic liver disease, n (%) 30 (7.8%) 16 (5.3%) 14 (16.7%) 0.002
Severe sepsis, n (%) 373 (96.4%) 290 (95.7%) 83 (98.8%) 0.319
Septic shock, n (%) 273 (70.5%) 207 (68.3%) 66 (78.6%) 0.079
ALI/ARDS, n (%) 162 (41.9%) 116 (38.3%) 46 (54.8%) 0.009
Free hemoglobin, mg/dl 20 (10, 30) 10 (10, 30) 20 (10, 40) 0.002
Haptoglobin, μg/ml 1132 (508, 2,890) 1234 (569, 3,037) 750 (404, 2,421) 0.008
Hemopexin, μg/ml 591 (383, 925) 616 (397, 934) 470 (303, 891) 0.012
  1. Data given as median (25th percentile, 75th percentile) or number (percentage) of patients. APACHE II, Acute Physiology and Chronic Health Evaluation; PRBC, packed red blood cells 48 hours prior to blood draw; ALI/ARDS, acute lung injury/acute respiratory distress syndrome.