Table 1 Baseline characteristics
From: Association between haptoglobin, hemopexin and mortality in adults with sepsis
Characteristic | Overall | Survivors | Non-survivors | P-value |
|---|---|---|---|---|
|  | n = 387 | n = 303 (78.2%) | n = 84 (21.8%) |  |
Age, years | 57 (48, 68) | 56 (47, 67) | 61 (54, 70) | 0.012 |
Men, n (%) | 216 (55.8%) | 164 (54.1%) | 52 (61.9%) | 0.217 |
APACHE II on enrollment | 28 (22, 33) | 26 (21, 32) | 31 (26, 36) | <0.001 |
On dialysis at enrollment, n (%) | 14 (3.6%) | 13 (4.3%) | 1 (1.2%) | 0.319 |
PRBC transfusion, n (%) | 90 (23.3%) | 65 (21.5%) | 25 (29.8%) | 0.144 |
Chronic liver disease, n (%) | 30 (7.8%) | 16 (5.3%) | 14 (16.7%) | 0.002 |
Severe sepsis, n (%) | 373 (96.4%) | 290 (95.7%) | 83 (98.8%) | 0.319 |
Septic shock, n (%) | 273 (70.5%) | 207 (68.3%) | 66 (78.6%) | 0.079 |
ALI/ARDS, n (%) | 162 (41.9%) | 116 (38.3%) | 46 (54.8%) | 0.009 |
Free hemoglobin, mg/dl | 20 (10, 30) | 10 (10, 30) | 20 (10, 40) | 0.002 |
Haptoglobin, μg/ml | 1132 (508, 2,890) | 1234 (569, 3,037) | 750 (404, 2,421) | 0.008 |
Hemopexin, μg/ml | 591 (383, 925) | 616 (397, 934) | 470 (303, 891) | 0.012 |