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Table 3 ROC analysis of plasma NGAL for dialysis requiring AKI

From: Plasma neutrophil gelatinase-associated lipocalin in acute kidney injury superimposed on chronic kidney disease after cardiac surgery: a multicenter prospective study

  Non-dialysis requiring AKI Dialysis requiring AKI AUC-ROC Cutoff (Youden) Sensitivity (Youden) Specificity (Youden) Cutoff (95% sensitivity) Specificity (95% sensitivity) Cutoff (95% specificity) Sensitivity (95% specificity)
  (n = 44) (n = 9) (95% CI) (ng/ml)    (ng/ml)   (ng/ml)  
pre 122.5 (71.3 to 241.5) 482.0 (178.4 to 531.0)# 0.77 472 67% 89% 75 30% 785 11%
(0.55 to 0.90)
0 h 125.0 (90.0 to 187.8) 162.0 (121.0 to 272.0) 0.66 254 44% 89% 61 5% 469 0%
(0.44 to 0.83)
2 h 143.0 (89.7 to 238.8) 268.0 (171.0 to 419.0)# 0.75 170 89% 61% 89 23% 861 0%
(0.54 to 0.88)
4 h 152.0 (92.9 to 228.8) 383.0 (235.0 to 619.5)# 0.81 220 89% 75% 100 27% 608 28%
  1. AKI, acute kidney injury; AUC-ROC, area under the curve operating characteristic curves; CI, confidence interval; NGAL, neutrophil gelatinase-associated lipocalin.