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Table 1 Patient characteristics and clinical outcomes

From: Plasma neutrophil gelatinase-associated lipocalin in acute kidney injury superimposed on chronic kidney disease after cardiac surgery: a multicenter prospective study

 

Non-CKD, Non-AKI

Non-CKD, AKI

CKD, Non-AKI

CKD, AKI

P- value

 

(n = 58)

(n = 20)

(n = 35)

(n = 33)

Age (y.o.)

67.5 (57.8 to 74.0)

64.5 (53.3 to 73.0)

74.0 (69.0 to 79.0)

69.0 (65.5 to 76.0)

0.0005

Male, n (%)

36 (62.1%)

16 (80.0%)

23 (65.7%)

17 (51.5%)

0.2

Diabetes, n (%)

24 (41.4%)

8 (40.0%)

15 (42.9%)

12 (36.4%)

0.95

Hypertension, n (%)

34 (58.6%)

15 (75.0%)

24 (68.6%)

22 (66.7%)

0.54

Preoperative

     

Serum Cre (mg/dl)

0.75 (0.61 to 0.83)

0.76 (0.67 to 0.89)

1.13 (1.01 to 1.38)

1.39 (1.01 to 1.96)

<0.0001

eGFR (ml/min/1.73 m2)

75.0 (67.2 to 82.1)

71.8 (64.1 to 83.6)

48.5 (35.3 to 53.4)

36.7 (26.1 to 53.0)

<0.0001

Plasma NGAL (ng/ml)

61.0 (42.2 to 2.4)

75.5 (61.0 to 121.0)

120.0 (66.7 to 224.0)

209.0 (106.5 to 492.0)

<0.0001

Operation

     

Operation time (minutes)

296 (259 to 358)

330 (280 to 478)

304 (257 to 362)

355 (289 to 420)

0.064

OPCAB, n (%)

11 (19.0%)

5 (25.0%)

10 (28.6%)

6 (18.2%)

0.67

CPB, n (%)

47 (81.0%)

15 (75.0%)

25 (71.4%)

27 (81.8)

0.67

CPB time (minutes)

151 (119 to 204)

168 (132 to 286)

149 (115 to 195)

170 (110 to 228)

0.4

Valve surgery, n (%)

17 (29.3%)

7 (35.0%)

15 (42.9%)

12 (36.4%)

0.62

CABG surgery, n (%)

7 (12.1%)

1 (5.0%)

1 (2.9%)

5 (15.2%)

0.27

Valve + CABG, n (%)

7 (12.1%)

4 (20.0%)

5 (14.3%)

5 (15.2%)

0.86

Aortic graft replacement, n (%)

12 (20.7%)

3 (15.0%)

2 (5.7%)

1 (3.0%)

0.05

Other, n (%)

4 (6.9%)

0 (0.0%)

2 (5.7%)

4 (12.1%)

0.48

Postoperative

     

Body weight gain (kg)

1.95 (0.77 to 3.30)

2.96 (1.33 to 4.73)

2.04 (1.07 to 3.93)

2.45 (0.64 to 3.88)

0.66

Need for RRT, n (%)

0 (0.0%)

2 (10.0%)

0 (0.0%)

7 (21.2%)

0.0001

ICU stay (day)

3 (2 to 4)

4 (2 to 10)

3 (2 to 4)

4 (2 to 10)

0.0077

  1. CABG, coronary artery bypass grafting; CKD, chronic kidney disease; CPB, cardiopulmonary bypass; OPCAB, off-pump coronary artery bypass grafting; RRT, renal replacement therapy.