Table 2 Factors independently associated with 60-day mortality between initially and secondarily adequate antibiotic therapy groups

Inadequate antibiotic therapy (reference)

0.63 (0.42 to 0.94)

0.02

Initial adequate antibiotic therapy

Secondary adequate antibiotic therapy

0.69 (0.37 to 1.27)

0.23

SAPSII per 10 points

1.65 (1.53 to 1.77)

<.0001

Female gender

0.70 (0.52 to 0.94)

0.02

At least one co-morbidity

1.49 (1.13 to 1.97)

0.005

Adequate antibiotic therapy on day 2 versus day 1

1.33 (0.92 to 1.93)

0.13

Adequate antibiotic therapy on day 3 versus day 1

1.29 (0.76 to 2.20)

0.35

Corticosteroids

0.98 (0.72 to 1.32)

0.87