Skip to main content

Table 2 Factors independently associated with 60-day mortality between initially and secondarily adequate antibiotic therapy groups

From: Initial use of one or two antibiotics for critically ill patients with community-acquired pneumonia: impact on survival and bacterial resistance

Multivariate analysis (n = 898) sHR (95% CI) P- value
Inadequate antibiotic therapy (reference) 0.63 (0.42 to 0.94) 0.02
Initial adequate antibiotic therapy
Secondary adequate antibiotic therapy 0.69 (0.37 to 1.27) 0.23
SAPSII per 10 points 1.65 (1.53 to 1.77) <.0001
Female gender 0.70 (0.52 to 0.94) 0.02
At least one co-morbidity 1.49 (1.13 to 1.97) 0.005
Adequate antibiotic therapy on day 2 versus day 1 1.33 (0.92 to 1.93) 0.13
Adequate antibiotic therapy on day 3 versus day 1 1.29 (0.76 to 2.20) 0.35
Corticosteroids 0.98 (0.72 to 1.32) 0.87
  1. 95% CI, 95% confidence interval; SAPSII, Simplified Acute Physiology Score version II; sHR, subdistribution hazard ratio.