TY - JOUR AU - Barbhaiya, R. H. AU - Knupp, C. A. AU - Forgue, S. T. AU - Matzke, G. R. AU - Guay, D. R. AU - Pittman, K. A. PY - 1990 DA - 1990// TI - Pharmacokinetics of cefepime in subjects with renal insufficiency JO - Clin Pharmacol Ther VL - 48 UR - https://doi.org/10.1038/clpt.1990.149 DO - 10.1038/clpt.1990.149 ID - Barbhaiya1990 ER - TY - JOUR AU - Smith, N. L. AU - Freebairn, R. C. AU - Park, M. A. AU - Wallis, S. C. AU - Roberts, J. A. AU - Lipman, J. PY - 2012 DA - 2012// TI - Therapeutic drug monitoring when using cefepime in continuous renal replacement therapy: seizures associated with cefepime JO - Crit Care Resusc VL - 14 ID - Smith2012 ER - TY - JOUR AU - Bresson, J. AU - Paugam-Burtz, C. AU - Josserand, J. AU - Bardin, C. AU - Mantz, J. AU - Pease, S. PY - 2008 DA - 2008// TI - Cefepime overdosage with neurotoxicity recovered by high-volume haemofiltration JO - J Antimicrob Chemother VL - 62 UR - https://doi.org/10.1093/jac/dkn256 DO - 10.1093/jac/dkn256 ID - Bresson2008 ER - TY - JOUR AU - Capparelli, F. J. AU - Diaz, M. F. AU - Hlavnika, A. AU - Wainsztein, N. A. AU - Leiguarda, R. AU - Del Castillo, M. E. PY - 1840 DA - 1840// TI - Cefepime- and cefixime-induced encephalopathy in a patient with normal renal function JO - Neurology VL - 2005 ID - Capparelli1840 ER - TY - JOUR AU - Chatellier, D. AU - Jourdain, M. AU - Mangalaboyi, J. AU - Ader, F. AU - Chopin, C. AU - Derambure, P. AU - Fourrier, F. PY - 2002 DA - 2002// TI - Cefepime-induced neurotoxicity: an underestimated complication of antibiotherapy in patients with acute renal failure JO - Intensive Care Med VL - 28 UR - https://doi.org/10.1007/s00134-001-1170-9 DO - 10.1007/s00134-001-1170-9 ID - Chatellier2002 ER - TY - JOUR AU - Garces, E. O. AU - de Azambuja, M. F. A. AU - da Silva, D. AU - Bragatti, J. A. AU - Jacoby, T. AU - Thome, F. S. PY - 2008 DA - 2008// TI - Renal failure is a risk factor for cefepime-induced encephalopathy JO - J Nephrol VL - 21 ID - Garces2008 ER - TY - JOUR AU - Grill, M. F. AU - Maganti, R. PY - 2008 DA - 2008// TI - Cephalosporin-induced neurotoxicity: clinical manifestations, potential pathogenic mechanisms, and the role of electroencephalographic monitoring JO - Ann Pharmacother VL - 42 UR - https://doi.org/10.1345/aph.1L307 DO - 10.1345/aph.1L307 ID - Grill2008 ER - TY - JOUR AU - Jallon, P. AU - Fankhauser, L. AU - Du Pasquier, R. AU - Coeytaux, A. AU - Picard, F. AU - Hefft, S. AU - Assal, F. PY - 2000 DA - 2000// TI - Severe but reversible encephalopathy associated with cefepime JO - Neurophysiol Clin VL - 30 UR - https://doi.org/10.1016/S0987-7053(00)00234-3 DO - 10.1016/S0987-7053(00)00234-3 ID - Jallon2000 ER - TY - JOUR AU - Lam, S. AU - Gomolin, I. H. PY - 2006 DA - 2006// TI - Cefepime neurotoxicity: case report, pharmacokinetic considerations, and literature review JO - Pharmacotherapy VL - 26 UR - https://doi.org/10.1592/phco.26.8.1169 DO - 10.1592/phco.26.8.1169 ID - Lam2006 ER - TY - JOUR AU - Maganti, R. AU - Jolin, D. AU - Rishi, D. AU - Biswas, A. PY - 2006 DA - 2006// TI - Nonconvulsive status epilepticus due to cefepime in a patient with normal renal function JO - Epilepsy Behav VL - 8 UR - https://doi.org/10.1016/j.yebeh.2005.09.010 DO - 10.1016/j.yebeh.2005.09.010 ID - Maganti2006 ER - TY - JOUR AU - Plensa, E. AU - Gallardo, E. AU - Ribera, J. M. AU - Batlle, M. AU - Oriol, A. AU - Costa, J. PY - 2004 DA - 2004// TI - Nonconvulsive status epilepticus associated with cefepime in a patient undergoing autologous stem cell transplantation JO - Bone Marrow Transplant VL - 33 UR - https://doi.org/10.1038/sj.bmt.1704314 DO - 10.1038/sj.bmt.1704314 ID - Plensa2004 ER - TY - JOUR AU - Sonck, J. AU - Laureys, G. AU - Verbeelen, D. PY - 2008 DA - 2008// TI - The neurotoxicity and safety of treatment with cefepime in patients with renal failure JO - Nephrol Dial Transplant VL - 23 UR - https://doi.org/10.1093/ndt/gfm713 DO - 10.1093/ndt/gfm713 ID - Sonck2008 ER - TY - JOUR AU - Barr, J. AU - Fraser, G. L. AU - Puntillo, K. AU - Ely, E. W. AU - Gélinas, C. AU - Dasta, J. F. AU - Davidson, J. E. AU - Devlin, J. W. AU - Kress, J. P. AU - Joffe, A. M. AU - Coursin, D. B. AU - Herr, D. L. AU - Tung, A. AU - Robinson, B. R. AU - Fontaine, D. K. AU - Ramsay, M. A. AU - Riker, R. R. AU - Sessler, C. N. AU - Pun, B. AU - Skrobik, Y. AU - Jaeschke, R. PY - 2013 DA - 2013// TI - Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the Intensive Care Unit JO - Crit Care Med VL - 41 UR - https://doi.org/10.1097/CCM.0b013e3182783b72 DO - 10.1097/CCM.0b013e3182783b72 ID - Barr2013 ER - TY - JOUR AU - Girard, T. D. AU - Pandharipande, P. P. AU - Ely, E. W. PY - 2008 DA - 2008// TI - Delirium in the intensive care unit JO - Crit Care Suppl VL - 3 UR - https://doi.org/10.1186/cc6149 DO - 10.1186/cc6149 ID - Girard2008 ER - TY - JOUR AU - Snavely, S. R. AU - Hodges, G. R. PY - 1984 DA - 1984// TI - The neurotoxicity of antibacterial agents JO - Ann Intern Med VL - 101 UR - https://doi.org/10.7326/0003-4819-101-1-92 DO - 10.7326/0003-4819-101-1-92 ID - Snavely1984 ER - TY - JOUR AU - Hocker, S. AU - Rabinstein, A. A. PY - 2011 DA - 2011// TI - A clinical and investigative approach to the patient with diminished responsiveness JO - Neurol Clin VL - 29 UR - https://doi.org/10.1016/j.ncl.2011.07.003 DO - 10.1016/j.ncl.2011.07.003 ID - Hocker2011 ER - TY - STD TI - FDA Drug Safety Communication: Cefepime and Risk of Seizure in Patients not Receiving Dosage Adjustments for Kidney Impairment. Available at: . Accessed April 26, 2013 http://www.fda.gov/Drugs/DrugSafety/ucm309661.htm Available at: . Accessed April 26, 2013 UR - http://www.fda.gov/Drugs/DrugSafety/ucm309661.htm ID - ref17 ER - TY - JOUR AU - Naeije, G. AU - Lorent, S. AU - Vincent, J. L. AU - Legros, B. PY - 2011 DA - 2011// TI - Continuous epileptiform discharges in patients treated with cefepime or meropenem JO - Arch Neurol VL - 68 UR - https://doi.org/10.1001/archneurol.2011.204 DO - 10.1001/archneurol.2011.204 ID - Naeije2011 ER - TY - JOUR AU - Gangireddy, V. G. AU - Mitchell, L. C. AU - Coleman, T. PY - 2011 DA - 2011// TI - Cefepime neurotoxicity despite renal adjusted dosing JO - Scand J Infect Dis VL - 43 UR - https://doi.org/10.3109/00365548.2011.581308 DO - 10.3109/00365548.2011.581308 ID - Gangireddy2011 ER - TY - JOUR AU - Yadla, M. AU - Kishore, C. K. AU - Sriramnaveen, P. AU - Reddy, Y. S. AU - Sainaresh, V. V. AU - Bhuma, V. AU - Sivakumar, V. PY - 2011 DA - 2011// TI - Neurotoxicity due to cefepime in patients on maintenance hemodialysis JO - Saudi J Kidney Dis Transpl VL - 22 ID - Yadla2011 ER - TY - JOUR AU - Chapuis, T. M. AU - Giannoni, E. AU - Majcherczyk, P. A. AU - Chioléro, R. AU - Schaller, M. D. AU - Berger, M. M. AU - Bolay, S. AU - Décosterd, L. A. AU - Bugnon, D. AU - Moreillon, P. PY - 2010 DA - 2010// TI - Prospective monitoring of cefepime in intensive care unit adult patients JO - Crit Care VL - 14 UR - https://doi.org/10.1186/cc8941 DO - 10.1186/cc8941 ID - Chapuis2010 ER - TY - JOUR AU - Durand-Maugard, C. AU - Lemaire-Hurtel, A. S. AU - Gras-Champel, V. AU - Hary, L. AU - Maizel, J. AU - Prud'homme-Bernardy, A. AU - Andréjak, C. AU - Andréjak, M. PY - 2012 DA - 2012// TI - Blood and CSF monitoring of cefepime-induced neurotoxicity: nine case reports JO - J Antimicrob Chemother VL - 67 UR - https://doi.org/10.1093/jac/dks012 DO - 10.1093/jac/dks012 ID - Durand-Maugard2012 ER -