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Table 3 Components of the FAB prediction model

From: Serum activin A and B levels predict outcome in patients with acute respiratory failure: a prospective cohort study

Variable Type   Equation factor
Age Numeric (Years)   0.041
Activin A, Activin B measurement at 2 days after commencement of ventilation – FAB Constructed variable Choice Activin A <0.283 ng/mL 0
Activin B <0.156 ng/mL
  Activin A >0.283 ng/mL OR 0.934
Activin B >0.156 ng/mL
  Activin A >0.283 ng/mL AND 1.197
Activin B >0.156 ng/mL
Chronic restrictive pulmonary disease Yes/No Yes 0.900
Chronic obstructive pulmonary disease Yes/No Yes 0.577
Diagnostic group Choice Postoperative cardiovascular 0
   Postoperative gastrointestinal 1.505
   Non-operative cardiovascular 2.135
   Non-operative sepsis 0.959
   Non-operative Gastrointestinal/hematological 1.111
   Non-operative metabolic 1.796
   Non-operative neurologic 2.599
   Non-operative respiratory 1.824
   Non-operative trauma 0.720
   Miscellaneous postoperative (respiratory, gynecologic, renal, orthopedic) 1.265
SOFA maximal score Numeric   0.220
Constant    -7.765
  1. FAB, follistatin, and activin A and B; SOFA: Sequential Organ Failure Assessment. Formula for FAB score: (Age*0.041) + (Activin A/B component) + (Presence of xhronic restrictive pulmonary disease) + (Presence of chronic obstructive pulmonary disease) + (Diagnostic group) + (Maximal SOFA score*0.220) + Constant. This produces a range with a mean of zero. To obtain the risk profile, each value was entered into the following equation: Probability Estimate = ln Result 1 + ln Result .
  2. This produced a range of values from 0.0 to 1.0, a score approaching 1.0 having the greatest risk of death and approaching 0.0 having the least risk of death. For risk stratification purposes, it was then divided into 10 bins, each 0.1 wide with the upper endpoint of each bin included in the lower bin.
  3. The equation factor listed is the value that should be inserted into the equation.