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Table 1 Preadmission patient characteristics and outcomes

From: Outcome and quality of life in patients with postoperative delirium during an ICU stay following major surgery

  All No delirium Delirium  
(n = 562) (n = 473) 84% (n = 89) 16% P
Admission and preadmission patient characteristics:     
 Age in years, median (IQR) 66 (54-74) 64 (53-73) 73 (61-81) <0.001a
 Age group, n (%)     <0.001b
   65 years 284 (51) 223 (47) 61 (69)  
   <65 years 278 (49) 250 (53) 28 (32)  
 Gender, n (%)     0.346b
   Male 354 (63) 294 (62) 60 (67)  
   Female 208 (37) 179 (38) 29 (33)  
 ASA physical status, n (%)     <0.001b
   I/II 189 (34) 175 (37) 14 (16)  
   III/IV 373 (66) 298 (63) 75 (84)  
 Body mass index in kg/m2, median (IQR) 25 (23-28) 25 (23-28) 26 (23-29) 0.231a
 Duration of anesthesia (min.), median (IQR) 240 (180-330) 240 (180-330) 240 (180-330) 0.343a
 Type of anesthesia, n (%)     0.903a
   General/combined general locoregional 476 (85) 401 (85) 75 (84)  
   Locoregional 86 (15) 72 (15) 14 (16)  
 Temperature at SICU admission, median (IQR) 35.0 (33.9-35.8) 35.0 (33.9-35.8) 35.0 (34.0-35.6) 0.905a
 Troponin I at SICU admission, median (IQR) 0.01(0.01-0.02) 0.01(0.01-0.01) 0.01(0.01-0.02) 0.001a
 Hypertension, n (%) 341 (61) 275 (58) 66 (74) 0.005b
 Hyperlipidemia, n (%) 224 (40) 175 (37) 49 (55) 0.001b
 COPD, n (%) 132 (24) 105 (22) 27 (30) 0.097b
 High-risk surgery, n (%) 294 (52) 247 (52) 47 (53) 0.919b
 Ischemic heart disease, n (%) 104 (19) 75 (16) 29 (33) <0.001b
 Congestive heart disease, n (%) 175 (31) 132 (28) 43 (48) <0.001b
 Cerebrovascular disease, n (%) 94 (17) 71 (15) 23 (26) 0.012b
 Renal insufficiency, n (%) 40 (7) 33 (7) 7 (8) 0.765b
 Insulin therapy for diabetes, n (%) 40 (7) 30 (6) 10 (11) 0.100b
 Total RCRI, n (%)     0.001b
   ≤2 487 (87) 420 (89) 67 (75)  
   >2 75 (13) 53 (11) 22 (25)  
 Crystalloids, median (IQR) 2511 (2000-4206) 2500 (2000-4148) 3000 (2000-4950) 0.324a
 Colloids, n (%) 176 (31) 143 (30) 33 (37) 0.201b
 Erythrocytes, n (%) 172 (31) 138 (29) 34 (38) 0.090b
 Fresh frozen plasma, n (%) 14 (3) 8 (2) 6 (7) 0.005b
 Platelets, n (%) 3 (1) 2 (0.4) 1 (1) 0.405b
Outcomes:     
 APACHE II score, median (IQR) 8 (5-11) 8 (5-10) 9 (7-12) <0.001a
 SICU length of stay (hours), median (IQR) 19 (16-30) 19 (15-23) 23 (18-71) <0.001a
 Hospital length of stay (days), median (IQR) 12 (5-24) 11 (5-23) 18 (9-35) <0.001a
 Mortality in SICU, n (%) 3 (1) 1 (0.2) 2 (2) 0.067b
 Mortality in hospital, n (%) 30 (5) 15 (3) 15 (17) <0.001b
 Mortality at six-month follow-up, n (%) 74 (13) 46 (10) 28 (32) <0.001b
  1. aMann-Whitney U test, bPearson χ2. IQR, interquartile range; ASA, American Society of Anesthesiologists; SICU, surgical intensive care unit; COPD, chronic obstructive pulmonary disease; RCRI, Revised Cardiac Risk Index; APACHE II, Acute Physiology and Chronic Health Evaluation II.