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Table 1 Preadmission patient characteristics and outcomes

From: Outcome and quality of life in patients with postoperative delirium during an ICU stay following major surgery

 

All

No delirium

Delirium

 

(n = 562)

(n = 473) 84%

(n = 89) 16%

P

Admission and preadmission patient characteristics:

    

 Age in years, median (IQR)

66 (54-74)

64 (53-73)

73 (61-81)

<0.001a

 Age group, n (%)

   

<0.001b

   65 years

284 (51)

223 (47)

61 (69)

 

   <65 years

278 (49)

250 (53)

28 (32)

 

 Gender, n (%)

   

0.346b

   Male

354 (63)

294 (62)

60 (67)

 

   Female

208 (37)

179 (38)

29 (33)

 

 ASA physical status, n (%)

   

<0.001b

   I/II

189 (34)

175 (37)

14 (16)

 

   III/IV

373 (66)

298 (63)

75 (84)

 

 Body mass index in kg/m2, median (IQR)

25 (23-28)

25 (23-28)

26 (23-29)

0.231a

 Duration of anesthesia (min.), median (IQR)

240 (180-330)

240 (180-330)

240 (180-330)

0.343a

 Type of anesthesia, n (%)

   

0.903a

   General/combined general locoregional

476 (85)

401 (85)

75 (84)

 

   Locoregional

86 (15)

72 (15)

14 (16)

 

 Temperature at SICU admission, median (IQR)

35.0 (33.9-35.8)

35.0 (33.9-35.8)

35.0 (34.0-35.6)

0.905a

 Troponin I at SICU admission, median (IQR)

0.01(0.01-0.02)

0.01(0.01-0.01)

0.01(0.01-0.02)

0.001a

 Hypertension, n (%)

341 (61)

275 (58)

66 (74)

0.005b

 Hyperlipidemia, n (%)

224 (40)

175 (37)

49 (55)

0.001b

 COPD, n (%)

132 (24)

105 (22)

27 (30)

0.097b

 High-risk surgery, n (%)

294 (52)

247 (52)

47 (53)

0.919b

 Ischemic heart disease, n (%)

104 (19)

75 (16)

29 (33)

<0.001b

 Congestive heart disease, n (%)

175 (31)

132 (28)

43 (48)

<0.001b

 Cerebrovascular disease, n (%)

94 (17)

71 (15)

23 (26)

0.012b

 Renal insufficiency, n (%)

40 (7)

33 (7)

7 (8)

0.765b

 Insulin therapy for diabetes, n (%)

40 (7)

30 (6)

10 (11)

0.100b

 Total RCRI, n (%)

   

0.001b

   ≤2

487 (87)

420 (89)

67 (75)

 

   >2

75 (13)

53 (11)

22 (25)

 

 Crystalloids, median (IQR)

2511 (2000-4206)

2500 (2000-4148)

3000 (2000-4950)

0.324a

 Colloids, n (%)

176 (31)

143 (30)

33 (37)

0.201b

 Erythrocytes, n (%)

172 (31)

138 (29)

34 (38)

0.090b

 Fresh frozen plasma, n (%)

14 (3)

8 (2)

6 (7)

0.005b

 Platelets, n (%)

3 (1)

2 (0.4)

1 (1)

0.405b

Outcomes:

    

 APACHE II score, median (IQR)

8 (5-11)

8 (5-10)

9 (7-12)

<0.001a

 SICU length of stay (hours), median (IQR)

19 (16-30)

19 (15-23)

23 (18-71)

<0.001a

 Hospital length of stay (days), median (IQR)

12 (5-24)

11 (5-23)

18 (9-35)

<0.001a

 Mortality in SICU, n (%)

3 (1)

1 (0.2)

2 (2)

0.067b

 Mortality in hospital, n (%)

30 (5)

15 (3)

15 (17)

<0.001b

 Mortality at six-month follow-up, n (%)

74 (13)

46 (10)

28 (32)

<0.001b

  1. aMann-Whitney U test, bPearson χ2. IQR, interquartile range; ASA, American Society of Anesthesiologists; SICU, surgical intensive care unit; COPD, chronic obstructive pulmonary disease; RCRI, Revised Cardiac Risk Index; APACHE II, Acute Physiology and Chronic Health Evaluation II.
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