Figure 4
From: Randomized controlled trials in pediatric critical care: a scoping review
Number of children randomized in 236 pediatric critical care randomized controlled trials (1986 to 2012). The center of each box indicates the median number of children randomized in the RCTs published in each year. The bottom and top of each box indicate the 1st and 3rd quartile respectively and the whiskers indicate the maximum and minimum values for RCTs in that year. An additional 12 trials published between January and April 2013.