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Table 3 Outcome characteristics of the 101 patients according to the initial treatment response

From: Procalcitonin biomarker kinetics fails to predict treatment response in perioperative abdominal infection with septic shock

 

All

Treatment success

Treatment failure

P

(n = 101)

(n = 65)

(n = 36)

Relaparotomy needed

21 (21)

3 (5)

18 (50)

<0.001

Surgical drainage after first line treatment

8 (8)

1 (1)

7 (19)

0.001

Duration of antibiotic treatment during ICU stay (days)

11.7 ± 7.2

11.3 ± 6.1

12.9 ± 8.8

0.84

Nosocomial infection

36 (36)

15 (23)

21 (58)

<0.001

Cytomegalovirus reactivation

5 (5)

2 (3)

3 (8)

0.24

Duration of mechanical ventilation (days)

8 ± 6

6 ± 7

9 ± 9

0.002

ICU length of stay (days)

11 ± 10

10 ± 9

14 ± 11

0.08

Mortality in the ICU

29 (29)

2 (3)

27 (75)

<0.001

Cause of death

    

  Refractory shock related to initial infection

5 (5)

0

5 (14)

<0.001

  Secondary surgical complication

7 (7)

0

7 (19)

<0.001

  Nosocomial infection as the main cause of death

4 (11)

0

4 (11)

<0.001

  Other including intensive care withdrawal

13 (13)

2 (3)

11 (31)

<0.001

  1. Continuous data are expressed as mean and standard deviation. Categorical data are expressed as number and percentage. ICU, intensive care unit.