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Table 4 Variables associated with renal outcomes

From: Effect of erythropoietin on the incidence of acute kidney injury following complex valvular heart surgery: a double blind, randomized clinical trial of efficacy and safety

Variable Control (number = 49) EPO (number = 49) P value
Postoperative AKI 16 (0.33, 0.26 to 0.39) 17 (0.35, 0.28 to 0.42) 0.831
 Stage 1 12 (0.25, 0.18 to 0.31) 12 (0.25, 0.18 to 0.31) 1.000
 Stage 2 0 0 1.000
 Stage 3 4 (0.08, 0.04 to 0.12) 5 (0.10, 0.06 to 0.15) 0.727
Postoperative dialysis 4 (0.08, 0.04 to 0.12) 5 (0.10, 0.06 to 0.15) 0.727
Serum creatinine (mg/dl)    0.090b
 Baseline 0.99 ± 0.27 0.92 ± 0.28 0.218
 ICU arrival 0.89 ± 0.25a 0.92 ± 0.34 0.546
 POD 1 1.13 ± 0.39a 1.08 ± 0.46a 0.588
 POD 2 1.09 ± 0.55 1.07 ± 0.50a 0.795
 POD 3 1.00 ± 0.54 0.96 ± 0.52 0.754
 POD 5 0.87 ± 0.35a 0.85 ± 0.52 0.934
Cystatin C (mg/L)    0.423b
 Baseline 1.13 ± 0.37 1.04 ± 0.28 0.191
 ICU arrival 1.00 ± 0.27a 0.95 ± 0.31 0.457
 POD 1 1.08 ± 0.36 1.09 ± 0.39 0.912
 POD 2 1.30 ± 0.54a 1.26 ± 0.57a 0.736
 POD 3 1.58 ± 0.89a 1.54 ± 0.88a 0.898
eGFR (mL/min/1.73 m2)    0.759b
 Baseline 77 ± 30 83 ± 28 0.381
 ICU arrival 89 ± 36a 94 ± 46a 0.556
 POD 1 80 ± 46 79 ± 43 0.941
 POD 2 72 ± 36 71 ± 30a 0.985
 POD 3 79 ± 35 76 ± 30 0.659
 POD 5 88 ± 32a 89 ± 30a 0.863
Log NGAL    0.891b
 Baseline 1.53 ± 0.28 1.56 ± 0.26 0.780
 1 hourr after ACC off 2.21 ± 0.26a 2.16 ± 0.28a 0.591
 6 hourr after ACC off 2.24 ± 0.33a 2.17 ± 0.33a 0.550
 24 hourr after operation 2.17 ± 0.37a 2.14 ± 0.36a 0.846
  1. Values are number of patients (probability, 95% confidence interval) or mean ± SD. aP <0.05, compared with baseline; bPgroup x time = P-value of the group and time interaction obtained by the linear mixed model. ACC, aortic cross clamp; AKI, acute kidney injury; eGFR, estimated glomerular filtration rate; EPO, erythropoietin; Log NGAL, logarithm of neutrophil gelatinase-associated lipocalin; POD, postoperative days.