Effect of erythropoietin on the incidence of acute kidney injury following complex valvular heart surgery: a double blind, randomized clinical trial of efficacy and safety

Table 2 Intraoperative parameters and fluid balance

Variable	Control (number = 49)	EPO (number = 49)	P value
Operation time (min)	253 ± 68	243 ± 63	0.480
CPB time (min)	129 ± 42	128 ± 39	0.870
ACC time (min)	96 ± 38	96 ± 30	0.894
Norepinephrine infused (μg)	70 (40 to 117)	68 (36 to 101)	0.350
Amount of ultrafiltration (ml)	1,000 (563 to 1,575)	1,000 (450 to 2,000)	0.936
Fluid balance during operation
crystalloid (ml)	1,570 ± 531	1,579 ± 487	0.934
colloid (ml)	500 (350 to 600)	450 (300 to 575)	0.398
urine output (ml)	1,022 ± 493	1,004 ± 505	0.863
Amount of pRBC transfusion (ml)	219 ± 384	122 ± 162	0.107
Amount of cell salvaged blood (ml)	550 (490 to 765)	500 (480 to 748)	0.268
Patients transfused with pRBCs (number)	20 (41)	21 (43)	0.838

Values are mean ± SD or median (25th to 75th). ACC, aorta cross clamp; CPB, cardiopulmonary bypass; EPO, erythropoietin; pRBCs, packed red blood cells.

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