Table 2 Comparison of plasma biomarker levels between 100 severe sepsis patients with ARDS (cases) and 100 severe sepsis patients without ARDS (controls)
Biomarker | Number | ARDS cases number = 100 | Controls number = 100 | P Value |
|---|---|---|---|---|
SP-D (ng/ml) | 200 | 86 (46 to 159) | 43 (28 to 77) | <0.001 |
RAGE (pg/ml) | 200 | 1,844 (1,060 to 3,737) | 1,232 (766 to 2147) | <0.001 |
IL-8 (pg/ml) | 200 | 27.2 (14.2 to 119.5) | 16.8 (9.3 to 45.6) | 0.006 |
CC16 (ng/ml) | 200 | 9.2 (5.0 to 15.8) | 13.1 (6.3 to 27.8) | 0.013 |
IL-6 (pg/ml) | 200 | 283 (92 to 803) | 142 (57 to 550) | 0.023 |
PCPIII (ug/ml) | 200 | 11.5 (6.9 to 18.7) | 11.5 (6.7 to 34.2) | 0.25 |
BNP (pg/ml) | 200 | 404 (264 to 748) | 412 (212 to 712) | 0.38 |
MMP-9 (ng/ml) | 195 | 151 (67 to 300) | 163 (81 to 337) | 0.39 |
MMP-1 (ng/ml) | 195 | 28 (15 to 51) | 31 (17 to 56) | 0.44 |
Ang2 (ng/ml) | 200 | 13 (7 to 21) | 12 (7 to 20) | 0.67 |
MMP-3 (ng/ml) | 195 | 22 (15 to 35) | 22 (14 to43) | 0.78 |