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Table 1 Baseline clinical characteristics of the total cohort and those with suspected ventilator associated respiratory infection (sVARI)

From: Suspected ventilator-associated respiratory infection in severely ill patients: a prospective observational study

 

Total cohort (267)

No VARI (190)

Suspected VARI (77)

P value

Median age (IQR)

55 (46 to 65)

55(46 to 67)

55(46 to 66)

0.77

Male sex (%)

166 (62.7)

116(61.1)

50(64.9)

0.55

Primary diagnosis at admission a

    

  Respiratory

51 (18.8)

30(15.8)

20(26.0)

0.05

  Cardiovascular

8 (3.0)

6(3.2)

2(2.6)

0.81

  Gastroenterological

20 (7.4)

14(7.4)

6(7.8)

0.91

  Neurological

3 (1.11)

3(1.6)

0

0.27

  Sepsis

45 (16.6)

29(15.3)

16(20.8)

0.28

  Post-operative

109 (40.2)

79(41.6)

28(36.4)

0.43

  Post arrest

8 (3.0)

8(4.2)

0

0.07

  Other

8 (3.0)

14 (7.4)

5(6.5)

0.80

Co-morbidities

    

  Diabetes

92 (34.0)

64(33.7)

26(33.8)

0.99

  COPD/Asthma

51 (18.8)

34(17.9)

17(22.1)

0.43

  CAD

132 (48.7)

94(49.5)

36(46.8)

0.69

  CHF

77 (28.4)

52(27.4)

25(32.5)

0.41

  Liver disease

54 (19.9)

38(20.0)

15(19.5)

0.92

  Malignancy

73 (26.9)

47(24.7)

25(32.5)

0.20

  Dementia

9 (3.3)

5(2.6)

4(5.2)

0.3

  Immunosuppressed

34 (12.7)

17 (9.0)

17(22.1)

0.004

  Stroke

29 (10.7)

23(12.1)

6(7.8)

0.31

CRF

75 (27.7)

52(27.4)

23(29.9)

0.68

APACHE II Score b (IQR)

27 (22 to 34)

27(21 to 36)

27(22 to 33)

0.83

  1. aNineteen patients had missing initial diagnoses; bAPACHE scores available for 64% of the cohort. The remainder of patients consisted of cardiac surgery admissions for which the APACHE score has not been validated. APACHE II, Acute Physiology and Chronic Health Evaluation II; COPD, chronic obstructive pulmonary disease; CAD, coronary artery disease; CHF, congestive heart failure; CRF, chronic renal failure; IQR, interquartile range.