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Table 1 Baseline clinical characteristics of the total cohort and those with suspected ventilator associated respiratory infection (sVARI)

From: Suspected ventilator-associated respiratory infection in severely ill patients: a prospective observational study

  Total cohort (267) No VARI (190) Suspected VARI (77) P value
Median age (IQR) 55 (46 to 65) 55(46 to 67) 55(46 to 66) 0.77
Male sex (%) 166 (62.7) 116(61.1) 50(64.9) 0.55
Primary diagnosis at admission a     
  Respiratory 51 (18.8) 30(15.8) 20(26.0) 0.05
  Cardiovascular 8 (3.0) 6(3.2) 2(2.6) 0.81
  Gastroenterological 20 (7.4) 14(7.4) 6(7.8) 0.91
  Neurological 3 (1.11) 3(1.6) 0 0.27
  Sepsis 45 (16.6) 29(15.3) 16(20.8) 0.28
  Post-operative 109 (40.2) 79(41.6) 28(36.4) 0.43
  Post arrest 8 (3.0) 8(4.2) 0 0.07
  Other 8 (3.0) 14 (7.4) 5(6.5) 0.80
Co-morbidities     
  Diabetes 92 (34.0) 64(33.7) 26(33.8) 0.99
  COPD/Asthma 51 (18.8) 34(17.9) 17(22.1) 0.43
  CAD 132 (48.7) 94(49.5) 36(46.8) 0.69
  CHF 77 (28.4) 52(27.4) 25(32.5) 0.41
  Liver disease 54 (19.9) 38(20.0) 15(19.5) 0.92
  Malignancy 73 (26.9) 47(24.7) 25(32.5) 0.20
  Dementia 9 (3.3) 5(2.6) 4(5.2) 0.3
  Immunosuppressed 34 (12.7) 17 (9.0) 17(22.1) 0.004
  Stroke 29 (10.7) 23(12.1) 6(7.8) 0.31
CRF 75 (27.7) 52(27.4) 23(29.9) 0.68
APACHE II Score b (IQR) 27 (22 to 34) 27(21 to 36) 27(22 to 33) 0.83
  1. aNineteen patients had missing initial diagnoses; bAPACHE scores available for 64% of the cohort. The remainder of patients consisted of cardiac surgery admissions for which the APACHE score has not been validated. APACHE II, Acute Physiology and Chronic Health Evaluation II; COPD, chronic obstructive pulmonary disease; CAD, coronary artery disease; CHF, congestive heart failure; CRF, chronic renal failure; IQR, interquartile range.