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Table 2 Areas under the curve of various parameters for predicting severe sepsis, septic shock and 28-day mortality in septic patients

From: Diagnostic value and prognostic evaluation of Presepsin for sepsis in an emergency department

 

Variable

AUC

Standard error

P value

95% confidence interval

     

Lower limit

Upper limit

Severe sepsis

Presepsin

0.840

0.016

0

0.809

0.872

 

Procalcitonin

0.741

0.019

0

0.703

0.779

 

MEDS score

0.818

0.017

0

0.785

0.851

 

APACHE II score

0.744

0.019

0

0.706

0.782

 

MEDS score + presepsina

0.875

0.014

0

0.848

0.901

 

APACHE II score + presepsinb

0.858

0.015

0

0.829

0.887

Septic shock

Presepsin

0.790

0.024

0

0.742

0.837

 

Procalcitonin

0.768

0.024

0

0.721

0.816

 

MEDS score

0.904

0.017

0

0.871

0.938

 

APACHE II score

0.820

0.023

0

0.774

0.865

 

MEDS score + presepsinc

0.924

0.014

0

0.897

0.951

 

APACHE II score + presepsind

0.868

0.019

0

0.831

0.905

28-day mortality

Presepsin

0.658

0.023

0

0.614

0.703

 

Procalcitonin

0.679

0.022

0

0.636

0.722

 

MEDS score

0.719

0.021

0

0.677

0.760

 

APACHE II score

0.722

0.021

0

0.681

0.763

 

MEDS score + presepsine

0.731

0.021

0

0.690

0.771

 

APACHE II score + presepsinf

0.734

0.021

0

0.693

0.775

  1. AUC, area under the receiver operating characteristic curve. aCompared with Mortality in Emergency Department Sepsis (MEDS) score, P <0.01. bCompared with Acute Physiology and Chronic Health Evaluation (APACHE) II score, P <0.01. cCompared with presepsin, P <0.01. dCompared with presepsin, P < 0.05. eCompared with presepsin, P <0.05. fCompared with presepsin, P <0.05.