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Table 4 Performance of the new termination-of-resuscitation rule for predicting one-month unfavorable neurological outcome a

From: Termination-of-resuscitation rule for emergency department physicians treating out-of-hospital cardiac arrest patients: an observational cohort study

  Development group (N= 390,577) Validation group (N= 105,030)
Variables Fulfilled 3/3 criteria Did not fulfill criteria Fulfilled 3/3 criteria Did not fulfill criteria
(n= 223,023, 57.1%) (n= 167,554, 42.9%) (n= 60,205, 57.3%) (n= 44,825, 42.7%)
Unfavorable (CPC categories 3 to 5), n 222,642 161,691 60,132 42,751
Favorable (CPC categories 1 and 2), n 381 5,863 73 2,074
Sensitivity (95% CI) 0.579 (0.578 to 0.581) 0.585 (0.582 to 0.588)
Specificity (95% CI) 0.939 (0.933 to 0.945) 0.966 (0.958 to 0.973)
PPV (95% CI) 0.998 (0.998 to 0.999) 0.999 (0.999 to 0.999)
NPV (95% CI) 0.035 (0.034 to 0.036) 0.046 (0.044 to 0.048)
Area under the ROC curve (95% CI) 0.922 (0.921 to 0.923) 0.942 (0.941 to 0.944)
  1. aCPC, Cerebral Performance Category; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; ROC, receiver operating characteristic.