Termination-of-resuscitation rule for emergency department physicians treating out-of-hospital cardiac arrest patients: an observational cohort study

Table 4 Performance of the new termination-of-resuscitation rule for predicting one-month unfavorable neurological outcome ^a

	Development group (N= 390,577)		Validation group (N= 105,030)
Variables	Fulfilled 3/3 criteria	Did not fulfill criteria	Fulfilled 3/3 criteria	Did not fulfill criteria
Variables	(n= 223,023, 57.1%)	(n= 167,554, 42.9%)	(n= 60,205, 57.3%)	(n= 44,825, 42.7%)
Unfavorable (CPC categories 3 to 5), n	222,642	161,691	60,132	42,751
Favorable (CPC categories 1 and 2), n	381	5,863	73	2,074
Sensitivity (95% CI)	0.579 (0.578 to 0.581)		0.585 (0.582 to 0.588)
Specificity (95% CI)	0.939 (0.933 to 0.945)		0.966 (0.958 to 0.973)
PPV (95% CI)	0.998 (0.998 to 0.999)		0.999 (0.999 to 0.999)
NPV (95% CI)	0.035 (0.034 to 0.036)		0.046 (0.044 to 0.048)
Area under the ROC curve (95% CI)	0.922 (0.921 to 0.923)		0.942 (0.941 to 0.944)

^aCPC, Cerebral Performance Category; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; ROC, receiver operating characteristic.

ISSN: 1364-8535