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Table 4 Arterial blood gases at baseline zero end-expiratory pressure and end a

From: Biphasic positive airway pressure minimizes biological impact on lung tissue in mild acute lung injury independent of etiology

  ALIp ALIexp
Arterial blood gases PCV BIVENT-100 BIVENT-75 BIVENT-50 PCV BIVENT-100 BIVENT-75 BIVENT-50
Baseline ZEEP         
PaO2 (mmHg) 177.5 ± 42.3 153.0 ± 39.2 162.0 ± 46.7 227.0 ± 56.6 149.7 ± 15.8 169.5 ± 31.8 181.8 ± 28.4 174.5 ± 26.5
PaCO2 (mmHg) 41.7 ± 5.1 42.0 ± 2.9 47.7 ± 2.3 42.2 ± 1.9 50.2 ± 6.6 43.4 ± 2.7 44.2 ± 3.2 42.1 ± 2.9
pHa 7.27 ± 0.03 7.31 ± 0.02 7.29 ± 0.02 7.30 ± 0.03 7.20 ± 0.03 7.27 ± 0.02 7.24 ± 0.04 7.29 ± 0.04
End         
PaO2 (mmHg) 457.7 ± 35.6 458.8 ± 16.9 410.5 ± 53.1 456.2 ± 35.3 393.7 ± 30.4 350.8 ± 20.9 395.8 ± 23.7 381.3 ± 7.6
PaCO2 (mmHg) 37.8 ± 5.1 43.1 ± 2.5 44.2 ± 4.3 41.8 ± 1.0 44.1 ± 1.6 43.2 ± 1.5 47.5 ± 3.9 48.4 ± 2.0
pHa 7.27 ± 0.03 7.31 ± 0.03 7.24 ± 0.05 7.29 ± 0.02 7.21 ± 0.02 7.20 ± 0.03 7.26 ± 0.04 7.27 ± 0.03
  1. aALIexp: extrapulmonary acute lung injury; ALIp: pulmonary acute lung injury; BIVENT: biphasic positive airway pressure at different rates of time-cycled controlled breaths: 100, 75 and 50 breaths/min; PaO2: partial pressure of arterial oxygen; PaCO2: partial pressure of arterial carbon dioxide; PCV: pressure-controlled ventilation;, pHa: arterial pH; ZEEP: zero end-expiratory pressure. PaO2, PaCO2 and pHa were measured at baseline ZEEP and after one hour of mechanical ventilation at a fraction of inspired oxygen = 1.0 in animals with ALIp and ALIexp. Values are means ± SEM of six rats.