Table 2 Baseline mechanical data a
Parameters | ALIp | ALIexp | |||||||
|---|---|---|---|---|---|---|---|---|---|
PCV | BIVENT-50 | BIVENT-75 | BIVENT-100 | PCV | BIVENT-50 | BIVENT-75 | BIVENT-100 | ||
RR (breaths/min) | C | 99 (99 to 99) | 42 (25 to 49) | 55 (0 to 72) | 96 (65 to 97) | 99 (98 to 99) | 22 (0 to 43) | 59 (32 to 73) | 69 (48 to 96) |
M | – | 0 (0 to 13) | 0 (0 to 73) | 0 (0 to 0) | – | 11.5 (0 to 48.0) | 0 (0 to 30.0) | 0 (0 to 0) | |
Phigh | – | 0 (0 to 4) | 0 (0 to 16) | 0 (0 to 30.0) | – | 1.5 (0 to 7) | 0 (0 to 0) | 11 (0-32) | |
Plow | – | 33 (0 to 49) | – | – | – | 0 (0 to 47) | 0 (0 to 55.0) | – | |
Total | 99 (99 to 99) | 80 (51 to 92) | 73 (73 to 73) | 97 (96 to 97) | 99 (98 to 99) | 50 (49 to 92) | 75 (73 to 111) | 96 (96 to 97) | |
Vt (ml) | C | 1.7 (1.6 to 1.8) | 1.4 (0.92 to 1.70) | 0.7 (0 to 1.4) | 1.5 (1.4 to 1.6) | 1.7 (1.5 to 1.8) | 1.17 (0 to 1.3) | 0.7 (0.4 to 1.4) | 1.3 (0.8 to 1.5) |
M | – | 0 (0 to 1.9) | 0 (0 to 1.8) | 0 (0 to 0) | – | 0.8 (0 to 1.8) | 0 (0 to 1.7) | 0 (0 to 0) | |
Phigh | – | 0 (0 to 1.7) | 0 (0 to 1.2) | 0 (0 to 1.6) | – | 0.7 (0 to 1.5) | 0 (0 to 0) | 0.5 (0 to 1.7) | |
Plow | – | 1.1 (0 to 1.5) | – | – | – | 0 (0 to 1.7) | 0 (0 to 2.2) | – | |
Total | 1.7 (1.6 to 1.8) | 1.5 (1.5 to 1.6) | 1.5 (1.0 to 1.8) | 1.6 (1.4 to 1.6) | 1.7 (1.5 to 1.8) | 1.6 (1.4 to 1.6) | 1.5 (1.3 to 1.7) | 1.3 (1.2 to 1.6) | |
V′e (ml/min) | C | 168 (159 to 177) | 51 (28 to 83) | 38 (0 to 101) | 141 (95 to 156) | 161 (130 to 182) | 33 (0 to 54) | 32 (23 to 102) | 82 (43 to 121) |
M | – | 0 (0 to 24.8) | 0 (0 to 139) | 0 (0 to 0) | – | 20 (0 to 73) | 0 (0 to 52) | 0 (0 to 0) | |
Phigh | – | 0 (0 to 6.8) | 0 (0 to 22) | 0 (0 to 54) | – | 2 (0 to 9) | 0 (0 to 0) | 19 (0 to 63) | |
Plow | – | 40 (0 to 67) | 0 (0 to 0) | 0 (0 to 0) | – | 0 (0 to 85) | 0 (0 to 136) | – | |
Total | 168 (159 to 177) | 107 (83 to 145) | 106 (72 to 139) | 150 (144 to 156) | 161 (130 to 182) | 85 (71 to 149) | 141 (102 to 160) | 121 (111 to 151) | |
Ppeak,aw (cmH2O) | C | 15.6 (14.2 to 18.8) | 11.8 (10.4 to 13.0) | 11.4 (11 to 12.1) | 15.5 (13.7 to 17.9) | 13.5 (13 to 14.7) | 10.8 (10.5 to 12.4) | 9.8 (9.3 to 12.5) | 13.3 (9.5 to 13.9) |
M | – | 11.1 (9.8 to 12.4) | 11.4 (11.0 to 11.9) | 15.2 (15.2 to 15.2) | – | 12.7 (11.4 to 12.9) | 10.5 (9.1 to 11.9) | 9.2 (9.2 to 9.2) | |
Pmean,aw (cmH2O) | C | 9.2 (8.3 to 10.0) | 7.6 (6.7 to 8.4) | 7.5 (7.4 to 7.7) | 10.5 (9.2 to 11.0) | 8.7 (8.5 to 9.5) | 7.6 (7.2 to 7.8) | 8.0 (7.6 to 8.1) | 9.1 (7.3 to 9.4) |
M | – | 6.6 (6.1 to 7.0) | 7.1 (6.7 to 7.5) | 9.1 (9.1 to 9.1) | – | 6.8 (6.6 to 7.0) | 6.8 (6.4 to 7.2) | 6.8 (6.8 to 6.8) | |
Ti/Ttot | C | 0.35 (0.35 to 0.36) | 0.36 (0.27 to 0.44) | 0.36 (0 to 0.39) | 0.50 (0.50 to 0.51) | 0.36 (0.35 to 0.37) | 0.27 (0 to 0.45) | 0.41 (0.38 to 0.51) | 0.51 (0.49 to 0.51) |
PEEP | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | |
PTP (cmH2O/ml) | M | – | 0 (0 to 38.7) | 0 (0 to 143.2) | 0 (0 to 0) | – | 0 (0 to 8.7) | 0 (0 to 54.3) | 0 (0 to 0) |
Phigh | – | 0 (0 to 3.2) | 0 (0 to 37.7) | 0 (0 to 38.2) | – | 0 (0 to 4.0) | 0 (0 to 0) | 22.0 (0 to 68.8) | |
Plow | – | 64.7 (0 to 134.5) | – | – | – | 0 (0 to 0) | 0 (0 to 168.2) | – | |
Total | – | 86.8 (76.4 to 137.7) | 67.4 (0 to 143.2) | 0 (0 to 38.2)b,c | – | 40.6 (9.3 to 57.6) | 90.5 (0 to 168.2) | 56.4 (0 to 113.0) | |
P0.1 (cmH2O) | M | – | 0 (0 to 0.3) | 0 (0 to 0.5) | 0 (0 to 0) | – | 0.1 (0 to 0.9) | 0 (0 to 1.4) | 0 (0 to 0) |
Phigh | – | 0 (0 to 1.2) | 0 (0 to 0.9) | 0 (0 to 0.6) | – | 0.2 (0 to 0.7) | 0 (0 to 0) | 0.4 (0 to 2.2) | |
Plow | – | 0.5 (0 to 0.7) | – | – | – | 0 (0 to 0.9) | 0 (0 to 2.9) | – | |