Neutrophils from critically ill septic patients mediate profound loss of endothelial barrier integrity

Table 1 Characteristics of septic patients

Primary sepsis vs. secondary sepsis	Primary sepsis	Secondary sepsis	P value
	(n= 12)	(n= 6)
Age (years)	59.9 ± 7.6	44 ± 7.8	0.2
Male sex (%)	58	50	0.9
Source of sepsis (%)
Abdominal	58	67	0.9
Pneumonia	42	33	0.9
White cell count (×10⁹ cells/l)	15.1 ± 1.1	18.1 ± 1.9	0.2
Neutrophil count (×10⁹ cells/l)	12.2 ± 0.9	12.6 ± 1.4	0.8
Septic patients with ARDS compared with those without evidence of ARDS	ARDS	No ARDS	P value
	( n = 6)	( n = 12)
Age (years)	57.5 ± 8.9	54.1 ± 6.7	0.8
Male sex (%)	50	58	0.9
Source of sepsis (%)
Abdominal	67	58	0.9
Pneumonia	33	42	0.9
White cell count (×10⁹ cells/l)	16.9 ± 2	15.7 ± 1.1	0.6
Neutrophil count (×10⁹ cells/l)	13.5 ± 1	11.8 ± 1	0.3

Characteristics listed are those on the day of study participation. Age, white blood cell count, and neutrophil count were analyzed using Student’s t test, and male sex and source of sepsis were analyzed using Fisher’s exact test. There were no differences between comparison groups. ARDS, acute respiratory distress syndrome.

ISSN: 1364-8535