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Table 2 Number of completed interventions and the time intervals from time zero to the implementation of each bundle component

From: The adverse effect of emergency department crowding on compliance with the resuscitation bundle in the management of severe sepsis and septic shock

 

Overall group

Low crowding group

Intermediate crowding group

High crowding group

P

(number = 770)

(number = 276)

(number = 250)

(number = 244)

Number of interventions of the bundle accomplishedc

5 (4 to 6)

6 (5 to 7)

6 (5 to 6)

5 (4 to 6)ab

<0.001

Time to the implementationd (hours)

     

 Serum lactate measurementc

1.3 (0.8)

1.2 (0.8 to 2.5)

1.3 (0.9 to 3.0)

1.4 (0.9 to 3.6)

0.023

 Blood culturesc

1.2 (0.8 to 2.1)

1.2 (0.8 to 1.9)

1.2 (0.8 to 2.3)

1.3 (0.9 to 2.2)

0.109

 Broad-spectrum antibioticsc

2.5 (1.7 to 3.8)

2.4 (1.5 to 3.5)

2.6 (1.7 to 3.9)

2.8 (1.8 to 4.2)

0.018

 Intravenous fluid challengec (n = 649)

0.6 (0.1 to 1.5)

0.6 (0.1 to 1.5)

0.6 (0.1 to 1.6)

0.8 (0.2 to 1.6)

0.109

 CVP ≥8 mmHg achievedc (n = 546)

2.9 (1.7 to 5.5)

2.5 (1.5 to 5.0)

2.7 (1.5 to 4.9)

3.5 (2.0 to 6.8)ab

0.005

 Use of vasopressorsc (n = 473)

2.1 (1.1 to 3.4)

1.8 (1.0 to 3.1)

1.9 (1.1 to 3.1)

2.4 (1.4 to 4.2)ab

0.003

 Scvo2 ≥70% achievedc (n = 573)

3.5 (1.9 to 6.6)

3.3 (1.7 to 5.7)

3.5 (2.0 to 5.8)

4.2 (1.9 to 6.5)

0.051

  1. Data are shown as median with interquartile range or number (%). aP <0.05 compared with the low crowding group after Bonferroni correction; bP <0.05 compared with the intermediate crowding group after Bonferroni correction; cP for trend <0.05 among the tertile groups; dcalculated beyond the specific time limits. CVP, central venous pressure; MAP, mean arterial pressure.