, mortality and Glu
in subgroups over time before and after NICE-SUGAR. Mean first day glucose (SE, Glu1, blue circles) in all patients with crude hospital mortality (SE, black squares) in four consecutive six-month periods before (periods 1 to 4) and after (periods 5 to 8) Normoglycemia in Intensive Care Evaluation and Surviving Using Glucose Algorithm Regulation (NICE-SUGAR) study (upper panel). Mean Glu1 values in patient subgroups (surgical/medical, IDDM/no IDDM, ICU stay >48 h/ICU stay <48 h) in the same six-month periods (lower panel). IDDM, insulin-dependent diabetes mellitus.