Continuous regional arterial infusion for acute pancreatitis: a propensity score analysis using a nationwide administrative database

Table 1 Japanese severity scoring system for acute pancreatitis of the Ministry of Health, Labour and Welfare of Japan (2008 revision) ^a

Scoring system	Basis for score
Prognostic factor score (one point for each factor)
1	Base excess less than or equal to -3 mEq/L or shock (systolic blood pressure below 80 mmHg)
2	PaO₂ ≤60 mmHg (room air) or respiratory failure (respiratory assistance needed)
3	BUN ≥40 mg/dl or (or creatinine ≥2.0 mg/dl) or oliguria (daily urine output <400 ml even after intravenous fluid resuscitation)
4	LDH at or above twice the upper limit of normal
5	Platelet count ≤100,000/mm³
6	Serum calcium ≤7.5 mg/dl
7	CRP ≥15 mg/dl
8	Number of positive measures in SIRS criteria ≥3
9	Age ≥70 years
CT grade based on contrast-enhanced CT
1	Extrapancreatic progression of inflammation
	Anterior pararenal space, zero points
	Root of mesocolon, one point
	Beyond lower pole of kidney, two points
2	Hypoenhanced lesion of the pancreas
	Pancreas conveniently divided into three segments (head, body and tail).
	Localized in each segment or surrounding only the pancreas, zero points
	Extends to two segments, one point
	Occupies two whole segments or more, two points
	Factors 1 + 2 = total score
	Total score = 0 or 1, grade 1
	Total score = 2, grade 2
	Total score = 3 or more, grade 3
Assessment of severity	If prognostic factor score is ≥3 or CT grade is ≥2, acute pancreatitis is considered severe.

^aBUN, Blood urea nitrogen; CRP, C-reactive protein; CT, Computed tomography; LDH, Lactate dehydrogenase; PaO₂, partial pressure of oxygen in blood; SIRS, Systemic inflammatory response syndrome. Measures within the SIRS criteria include body temperature above 38°C or less than 36°C, heart rate more than 90 beats/min, respiratory rate more than 20 breaths/min or partial pressure of carbon dioxide in blood less than 32 torr, as well as white blood cell count above 12,000 cells/mm³, less than 4,000 cells/mm³ or greater than 10% immature (band) forms. The 2008 revision of the Japanese severity scoring system is contained in [22].

ISSN: 1364-8535