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Figure 1 | Critical Care

Figure 1

From: Early treatment with IgM-enriched intravenous immunoglobulin does not mitigate critical illness polyneuropathy and/or myopathy in patients with multiple organ failure and SIRS/sepsis: a prospective, randomized, placebo-controlled, double-blinded trial

Figure 1

Study timeline. Patients with multiple (≥2) organ failure and a diagnosis of SIRS/sepsis were randomized to be treated either with intravenous immunoglobulins (IVIG) or human albumin (placebo) for three consecutive days. Critical illness polyneuropathy and/or myopathy (CIPNM) was assessed at baseline (Day 0) and on Day 14 by electrophysiological stimulation and histological assessment of a muscle biopsy. Primary endpoint was a CIPNM severity sum score on Day 14.

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Critical Care

ISSN: 1364-8535