Skip to main content

Table 2 Comparison of demographic characteristics and septic-shock severity between patients with normal MRI, isolated ischemic stroke, and leukoencephalopathy

From: Pattern of Brain Injury in the Acute Setting of Human Septic Shock

 

Total

Normal

Leukoencephalopat hy

Ischemia

P

 

63

37

10

16

 

Demographics

     

Age (years)

64 (55-75)

61 (48-78)

69 (67-75)

65 (63-74)

0.15

Women

25 (40)

12 (32)

4 (40)

9 (56)

0.30

Cardiovascular risk factors

37 (59)

19 (51)

8 (80)

10 (62)

0.25

Admission

     

SAPS II

49 (38-60)

52 (39-60)

49 (31-60)

48 (38-55)

0.79

Admission to MRI

     

Highest SOFA

13 (9-16)

13 (8-15)

9 (8-12)

15 (13-16)

0.05

Highest CV SOFA

3 (3-4)

3 (3-4)

2 (2-3)

4 (3-4)

0.48

Highest nonneuro SOFA (without GCS)

10 (7-12)

10 (6-12)

8 (5-8)

11 (9-12)

0.16

Lowest MBP (mm Hg)

52 (45-55)

51 (45-56)

53 (47-63)

52 (41-54)

0.67

Cumulative time with MBP <60 mm Hg (hours)

6 (3-8)

6 (3-11)

2 (1-7)

6 (5-8)

0.27

Highest plasma PTT level

1.8 (1.4-3.2)

1.4 (1.7-3.2)

2.0 (1.3-2.2)

2.5 (1.6-4.2)

0.06

Lowest plasma platelets level (109/L)

97 (47-224)

110 (51-223)b

228 (101-351)c

50 (23-95)

0.004

DIC

28 (44)

17 (46)

2 (20)

11 (69)

0.04

After MRI

     

Mortality

21 (33)

9 (24)b

2 (20)c

10 (62)

0.02

GOS 6 months ≤ 3

30 (48)

14 (38)b

3 (30)c

13 (81)

0.007

  1. Data are expressed in number (%) or median (IQR). Kruskal-Wallis and Mann-Whitney tests were used for comparison of quantitative variables between three and two groups. aSignificant difference between MRI normal and leukoencephalopathy. bSignificant difference between MRI normal and ischemia. cSignificant difference between MRI ischemia and leukoencephalopathy.
  2. SAPS-II, New Simplified Acute Physiology Score; MRI, magnetic resonance imaging; SOFA, Sepsis-related Organ Failure Assessment; CV, cardiovascular; MBP, mean blood pressure; PTT, partial thromboplastin time; DIC, disseminated intravascular coagulation; GOS, Glasgow Outcome Scale.