Table 1 Main characteristics between admission, inclusion, and after hospital discharge
From: Pattern of Brain Injury in the Acute Setting of Human Septic Shock
Variables | N= 71 |
|---|---|
Admission | |
Women | 27 (38) |
Age (years) | 65 (56-76) |
Cardiovascular risk factors (%) Atrial fibrillation (%) | 40 (56) 11 (16) |
Blood culture (%) | 17 (24) |
Pneumonia | 42 (59) |
Pathogens | |
Pure Gram negative | 28 (39) |
Pure Gram positive | 16 (23) |
SAPS II at admission | 49 (38-60) |
Knaus (B or more) | 56 (79) |
Mac Cabe (>1) | 29 (41) |
Admission to MRI | |
Delay from admission to MRI (days) | 7 (2-10) |
Delay from neurologic signs to MRI (days) | 3 (1-5) |
Highest SOFA (from 0 to 24) | 13 (9-16) |
Highest neurologic SOFA score (from 0 to 4) | 4 (2-4) |
Highest respiratory SOFA score (from 0 to 4) | 3 (2-3) |
Highest cardiovascular SOFA score (from 0 to 4) | 3 (3-4) |
Cumulative time with MBP <60 mm Hg (hours) | 5 (2-8) |
Highest hepatic SOFA score (from 0 to 4) | 1 (0-2) |
Highest renal SOFA score (from 0 to 4) | 1 (0-2) |
Presence of DIC (%) | 34 (48) |
Highest coagulation SOFA score (from 0 to 4) | 2 (0-3) |
Lowest/highest plasma sodium level (mM) | 134 (129-136)/144 (140-148) |
Lowest/highest plasma glucose level (mM) | 4·6 (3.6-5.1)/12.5 (10.0-16.9) |
Highest plasma lactate level (mM) | 4.3 (2.4-6.0) |
Lowest plasma platelets level (109/L) | 96 (45-220) |
Time on vasopressors (days) | 4 (2-8) |
Mean (nor)epinephrine infusion rate (μg/kg/min) | 0.83 (0.71 - 1.62) |
Insulin therapy (%) | 59 (83) |
Sedation (%) Mean midazolam infusion rate (mg/h) | 49 (69) 7.3 (5.1-9.0) |
Duration of sedation (days) | 2 (0-5) |
After MRI | |
Length of mechanical ventilation (days) | 21 (6-45) |
Length of stay in the ICU (days) | 31 (14-53) |
Mortality | 23 (32) |
GOS at 6 months >3(%) | 37 (52) |