Table 4 Peritoneal fluid cytokines (pg/ml) at Day 1, according to peritoneal fluid culture
From: Local and systemic innate immune response to secondary human peritonitis
Monomicrobial (number = 34) | Polymicrobial (number = 32) | P value | |
|---|---|---|---|
IL-1 | 8,194 (3,115 to 31,440) | 4,400 (509 to 16,730) | 0.09 |
TNFα | 290 (89 to 1,185) | 260 (93 to 695) | 0.42 |
IL-6 | 72,390 (13,760 to 201,600) | 236,800 (86,670 to 383,700) | 0.02 |
IL-10 | 550 (243 to 4,246) | 1,505 (320 to 2,610) | 0.78 |
IFNγ | 3 (1 to 23) | 2 (1 to 7) | 0.23 |
No anaerobes (number = 44) | Anaerobes (n = 12) | ||
IL-1 | 4,682 (1,000 to 19,220) | 26,000 (7,282 to 54,890) | 0.04 |
TNFα | 252 (95 to 851) | 805 (88 to 1,009) | 0.54 |
IL-6 | 164,400 (25,380 to 328,400) | 156,800 (1,536 to 270,300) | 0.44 |
IL-10 | 1,252 (386 to 2,785) | 370 (167 to 4,380) | 0.96 |
IFNγ | 2 (1 to 6) | 10 (5 to 28) | 0.01 |
No Enterococcus sp . (number = 43) | Enterococcus sp . (number = 13) | ||
IL-1 | 4,850 (1,000 to 22,580) | 8,528 (1,850 to 38,880) | 0.33 |
TNFα | 265 (96 to 848) | 185 (87 to 1,592) | 0.89 |
IL-6 | 195,600 (25,460 to 342,800) | 51,400 (12,800 to 190,000) | 0.12 |
IL-10 | 1,755 (403 to 3,679) | 435 (167 to 480) | 0.01 |
IFNγ | 2 (1 to 6) | 7 (2 to 39) | 0.05 |
No yeast (number = 57) | Yeast (number = 9) | ||
IL-1 | 7,859 (1,417 to 27,090) | 3,010 (840 to 4,693) | 0.25 |
TNFα | 285 (90 to 953) | 120 (96 to 530) | 0.37 |
IL-6 | 143,300 (20,630 to 348,300) | 196,800 (98,600 to 215,100) | 0.88 |
IL-10 | 1,252 (358 to 2,902) | 465 (40 to 2,292) | 0.34 |
IFNγ | 3 (2 to 9) | 2 (1 to 4) | 0.16 |