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Table 3 EA, thrombelastometric and aggregometric findings, conventional clotting variables in SIRS and sepsis patients

From: Systemic endotoxin activity correlates with clot formation: an observational study in patients with early systemic inflammation and sepsis

Ā 

SIRS

Sepsis

Ā 

Variables

Value

Value

P

EA

0.27 (0.14 to 0.52)

0.27 (0.01/0.72)

NS

CFT (sec)

263 (150 to 1,438)

268 (60/942)

NS

CT (sec)

906 (648 to 1,380)

1027 (53 to 1,481)

NS

Alpha-angle (Ā°)

50 (24 to 69)

47 (17 to 78)

NS

MCF (mm)

53 (24 to 67)

57 (5 to 76)

NS

LI60 (60%)

98 (90 to 100)

99 (93 to 100)

NS

ASPI (AUC (AU*min))

506 (49 to 1,137)

772 (21 to 1,667)

NS

ADP (AUC (AU*min))

539 (125 to 804)

504 (18 to 1,176)

NS

TRAP (AUC (AU*min))

799 (339 to 1,494)

887 (122 to 1,831)

NS

Platelets (Ɨ109/L)

131 (61 to 257)

166 (17 to 523)

NS

INR

1.40 (1.14 to 3.58)

1.37 (1.04 to 2.12)

NS

APPT (sec)

44 (38 to 112)

45 (32 to 79)

NS

Thrombin time (sec)

17 (14 to 95)

16 (14 to 79)

NS

Fibrinogen (mg/dL)

392 (60 to 829)

451 (112 to 1,106)

NS

Antithrombin (%)

57 (31 to 90)

62 (27 to 88)

NS

  1. ADP, adenosine diphosphate activated aggregometric analysis; aPPT, activated partial thromboplastin time; median (min-max); ASPI, arachidonic acid activated aggregometric analysis; CFT, clotting formation time; CT, clotting time; EA, endotoxin activity; INR, international normalized ratio; LI60, 60-minute lyses index; MCF, maximum clot firmness; TRAP, thrombin receptor activating peptide 6 activated aggregometric analysis