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Table 5 Settings, delivered ventilation, respiratory mechanics and blood gas results according to the lung condition in active patients.

From: Feasibility study on full closed-loop control ventilation (IntelliVent-ASV) in ICU patients with acute respiratory failure: a prospective observational comparative study

  1 Normal lung 2 ARDS 3 COPD 4 Others P (ANOVA) Post hoc comparison (P ≤0.05)
Number of patients 33 13 18 15   
Number of days 76 54 57 44   
MV (L/min) 10.1 (8.0-13.0) 12.5 (11.0-14.9) 11.1 (8.3-13.9) 9.2 (7.2-12.0) <0.001 1 vs. 2; 2 vs.
VT/PBW (mL/kg) 8.4 (7.8-9.1) 8.1 (7.5-9.3) 9.3 (8.6-11.6) 7.7 (7.2-9.3) <0.001 1 vs. 3; 2 vs. 3; 3 vs. 4
PEEP (cmH2O) 5 (5-5) 8 (5-10) 7 (5-10) 7 (5-10) <0.001 1 vs. 2; 1 vs. 3; 1 vs. 4
FiO2 (%) 30 (30-30) 33 (30-38) 30 (30-33) 30 (30-34) <0.001 1 vs. 2
PINSP (cmH2O) 21 (16-26) 24 (16-28) 22 (17-36) 24 (21-28) 0.052  
RR (breath/min) 21 (18-26) 25 (20-29) 18 (14-20) 21 (17-26) <0.001 1 vs. 3; 2 vs. 3; 3 vs. 4
RCEXP (s) 0.66 (0.51-0.78) 0.52 (0.45-0.61) 0.86 (0.64-1.12) 0.53 (0.46-0.65) <0.001 1 vs. 2; 1 vs. 3; 2 vs. 3; 3 vs. 4
PaO2/FiO2 (mm Hg) 322 (278-387) 213 (173-250) 273 (206-341) 253 (222-311) <0.001 1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3; 2 vs. 4
PaO2 (mm Hg) 102 (85-121) 77 (70-84) 89 (72-107) 83 (75-94) <0.001 1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3
pH 7.38 (7.34-7.44) 7.40 (7.35-7.43) 7.33 (7.25-7.37) 7.37 (7.30-7.42) <0.001 1 vs. 3; 2 vs. 3; 3 vs. 4
PaCO2 (mm Hg) 32 (28-37) 37 (30-40) 41 (34-50) 36 (32-44) <0.001 1 vs. 3; 1 vs. 4
  1. Values represent the median of all data. Comparisons used a Kruskal-Wallis analysis of variance (ANOVA) with a Dunn's post hoc test. MV, minute volume, VT/PBW, tidal volume on predicted body weight ratio, PEEP, positive end-expiratory pressure, PINSP, peak inspiratory pressure, RR, respiratory rate, RCEXP, expiratory time constant, vs., versus.