Skip to main content

Table 3 Settings, delivered ventilation, respiratory mechanics and blood gas results according to the lung condition in all patients.

From: Feasibility study on full closed-loop control ventilation (IntelliVent-ASV) in ICU patients with acute respiratory failure: a prospective observational comparative study

 

1

Normal lung

2

ARDS

3

COPD

4

Others

P (ANOVA)

Post hoc comparison (P ≤0.05)

Number of patients

45

16

19

20

  

Number of days

139

90

79

84

  

MV (L/min)

9.3 (7.5-11.7)

9.7 (7.8-13.3)

9.4 (6.4-11.9)

7.5 (6.6-10.8)

0.001

1 vs. 4

VT/PBW (mL/kg)

8.3 (7.7-9.1)

7.8 (7.2-8.5)

9.4 (8.4-11.5)

8.0 (7.3-9.2)

<0.001

1 vs. 3; 2 vs. 3; 3 vs. 4

PEEP (cmH2O)

5 (5-6)

9 (5-12)

7 (5-10)

8 (5-11)

<0.001

1 vs. 2; 1 vs. 3; 1 vs. 4

FiO2 (%)

30 (30-30)

34 (30-43)

31 (30-36)

30 (30-41)

<0.001

1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3

PINSP (cmH2O)

21 (18-25)

25 (20-30)

24 (19-38)

26 (22-30)

<0.001

1 vs. 2; 1 vs. 3; 1 vs. 4

RR (breath/min)

19 (16-23)

20 (16-26)

15 (12-19)

18 (14-22)

<0.001

1 vs. 3; 2 vs. 3; 2 vs. 4

RCEXP (s)

0.61 (0.50-0.75)

0.50 (0.43-0.58)

0.91 (0.64-1.22)

0.56 (0.46-0.66)

<0.001

1 vs. 2; 1 vs. 3; 2 vs. 3; 3 vs. 4

PaO2/FiO2 (mm Hg)

326 (267-380)

206 (172-252)

260 (206-328)

241 (189-304)

<0.001

1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3; 2 vs. 4

PaO2 (mm Hg)

100 (85-117)

76 (69-84)

86 (74-105)

82 (73-95)

<0.001

1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3; 2 vs. 4

pH

7.36 (7.30-7.41)

7.35 (7.23-7.42)

7.30 (7.25-7.35)

7.33 (7.26-7.41)

<0.001

1 vs. 3; 2 vs. 3

PaCO2 (mm Hg)

35 (31-40)

41 (35-49)

45 (37-53)

39 (34-46)

<0.001

1 vs. 2; 1 vs. 3; 1 vs. 4

  1. Values represent the median of all data. Comparisons used a Kruskal-Wallis analysis of variance (ANOVA) with a Dunn's post hoc test. MV, minute volume, VT/PBW, tidal volume on predicted body weight ratio, PEEP, positive end-expiratory pressure, PINSP, peak inspiratory pressure, RR, respiratory rate, RCEXP, expiratory time constant, vs., versus.