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Table 3 Settings, delivered ventilation, respiratory mechanics and blood gas results according to the lung condition in all patients.

From: Feasibility study on full closed-loop control ventilation (IntelliVent-ASV) in ICU patients with acute respiratory failure: a prospective observational comparative study

  1 Normal lung 2 ARDS 3 COPD 4 Others P (ANOVA) Post hoc comparison (P ≤0.05)
Number of patients 45 16 19 20   
Number of days 139 90 79 84   
MV (L/min) 9.3 (7.5-11.7) 9.7 (7.8-13.3) 9.4 (6.4-11.9) 7.5 (6.6-10.8) 0.001 1 vs. 4
VT/PBW (mL/kg) 8.3 (7.7-9.1) 7.8 (7.2-8.5) 9.4 (8.4-11.5) 8.0 (7.3-9.2) <0.001 1 vs. 3; 2 vs. 3; 3 vs. 4
PEEP (cmH2O) 5 (5-6) 9 (5-12) 7 (5-10) 8 (5-11) <0.001 1 vs. 2; 1 vs. 3; 1 vs. 4
FiO2 (%) 30 (30-30) 34 (30-43) 31 (30-36) 30 (30-41) <0.001 1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3
PINSP (cmH2O) 21 (18-25) 25 (20-30) 24 (19-38) 26 (22-30) <0.001 1 vs. 2; 1 vs. 3; 1 vs. 4
RR (breath/min) 19 (16-23) 20 (16-26) 15 (12-19) 18 (14-22) <0.001 1 vs. 3; 2 vs. 3; 2 vs. 4
RCEXP (s) 0.61 (0.50-0.75) 0.50 (0.43-0.58) 0.91 (0.64-1.22) 0.56 (0.46-0.66) <0.001 1 vs. 2; 1 vs. 3; 2 vs. 3; 3 vs. 4
PaO2/FiO2 (mm Hg) 326 (267-380) 206 (172-252) 260 (206-328) 241 (189-304) <0.001 1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3; 2 vs. 4
PaO2 (mm Hg) 100 (85-117) 76 (69-84) 86 (74-105) 82 (73-95) <0.001 1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3; 2 vs. 4
pH 7.36 (7.30-7.41) 7.35 (7.23-7.42) 7.30 (7.25-7.35) 7.33 (7.26-7.41) <0.001 1 vs. 3; 2 vs. 3
PaCO2 (mm Hg) 35 (31-40) 41 (35-49) 45 (37-53) 39 (34-46) <0.001 1 vs. 2; 1 vs. 3; 1 vs. 4
  1. Values represent the median of all data. Comparisons used a Kruskal-Wallis analysis of variance (ANOVA) with a Dunn's post hoc test. MV, minute volume, VT/PBW, tidal volume on predicted body weight ratio, PEEP, positive end-expiratory pressure, PINSP, peak inspiratory pressure, RR, respiratory rate, RCEXP, expiratory time constant, vs., versus.