From: Ideal resuscitation pressure for uncontrolled hemorrhagic shock in different ages and sexes of rats
Group | Baseline | End of phase I | End of phase II | End of phase III | End of phase IV |
---|---|---|---|---|---|
6 weeks old | Â | Â | Â | Â | Â |
Female | Â | Â | Â | Â | Â |
  No treatment | 5,454.1 ± 717.6 | 2,474.2 ± 325.5 | 2,371.1 ± 311.9 | 2,272.3 ± 298.9 | 2,177.6 ± 286.5 |
  40 mmHg | 5,461.8 ± 718.6 | 2,477.2 ± 325.9 | 3,400.0 ± 578.9** | 4,569.5 ± 601.2** | 5,045.9 ± 663.9** |
  50 mmHg | 5,905.4 ± 1,362.2 | 2,314.5 ± 1,114.4 | 4,663.8 ± 918.0**# | 4,777.2 ± 903.7** | 5,275.2 ± 601.9** |
  60 mmHg | 5,476.4 ± 720.5 | 2,482.9 ± 326.7 | 4,602.1 ± 605.5**# | 4,453.3 ± 585.9** | 4,878.6 ± 641.9** |
  70 mmHg | 5,410.0 ± 788.7 | 2,456.9 ± 645.3 | 4,776.7 ± 1,111.0**# | 4,420.9 ± 1,015.7** | 4,821.9 ± 932.0** |
  80 mmHg | 5,547.3 ± 729.9 | 2,510.8 ± 330.3 | 4,525.3 ± 595.4**# | 4,188.2 ± 551.0** | 4,568.2 ± 601.0**# |
Male | Â | Â | Â | Â | Â |
  No treatment | 5,417.0 ± 712.7 | 2,118.5 ± 278.7 | 2,030.2 ± 267.1 | 1,945.7 ± 256.0 | 1,864.6 ± 245.3 |
  40 mmHg | 5,424.8 ± 713.7 | 2,121.2 ± 279.1 | 3,519.6 ± 528.9** | 4,404.9 ± 579.6** | 4,943.3 ± 650.4** |
  50 mmHg | 5,938.1 ± 833.1 | 2,013.5 ± 681.6 | 4,278.2 ± 538.1** | 4,605.2 ± 398.8** | 5,168.0 ± 459.9** |
  60 mmHg | 5,439.4 ± 715.7 | 2,126.1 ± 279.7 | 4,251.1 ± 559.3** | 4,525.9 ± 595.5** | 4,842.5 ± 637.1** |
  70 mmHg | 5,372.7 ± 638.0 | 2,103.5 ± 522.0 | 4,328.0 ± 386.0** | 4,518.0 ± 499.0** | 4,796.0 ± 558.0** |
  80 mmHg | 5,510.8 ± 725.1 | 2,150.3 ± 282.9 | 4,100.2 ± 539.5** | 4,280.2 ± 563.1** | 4,543.5 ± 597.8** |
14 weeks old | Â | Â | Â | Â | Â |
Female | Â | Â | Â | Â | Â |
  No treatment | 5,925.4 ± 779.6 | 2,750.0 ± 361.8 | 2,635.4 ± 346.7 | 2,525.6 ± 332.3 | 2,420.3 ± 318.4 |
  40 mmHg | 5,933.7 ± 780.7 | 2,753.5 ± 362.3 | 3,491.2 ± 590.9** | 5,068.1 ± 666.8** | 4,898.9 ± 644.6** |
  50 mmHg | 6,369.5 ± 1,402.5 | 2,654.6 ± 1,147.7 | 4,232.5 ± 731.3** | 5,298.4 ± 930.4** | 5,121.6 ± 268.0** |
  60 mmHg | 5,949.4 ± 782.8 | 2,760.0 ± 363.1 | 4,852.7 ± 638.5** | 4,943.2 ± 650.4** | 4,932.7 ± 649.0** |
  70 mmHg | 5,877.8 ± 927.1 | 2,730.2 ± 758.5 | 4,392.3 ± 1,007.3** | 4,907.7 ± 1,578.3** | 4,905.7 ± 1,407.8** |
  80 mmHg | 6,026.0 ± 792.8 | 2,791.9 ± 367.3 | 4,161.1 ± 547.5** | 4,649.4 ± 611.7** | 4,647.5 ± 611.5** |
Male | Â | Â | Â | Â | Â |
  No treatment | 6,689.7 ± 880.2 | 2,321.2 ± 305.4 | 2,224.5 ± 292.7 | 2,131.8 ± 280.5 | 2,042.9 ± 268.8 |
  40 mmHg | 6,698.2 ± 881.3 | 2,324.1 ± 305.8 | 3,379.9 ± 576.3** | 4,696.6 ± 617.9** | 4,592.4 ± 604.2** |
  50 mmHg | 6,495.3 ± 1,417.3 | 2,231.5 ± 660.0 | 4,660.1 ± 413.9**# | 4,910.0 ± 910.3** | 4,801.1 ± 645.3** |
  60 mmHg | 6,714.2 ± 883.4 | 2,329.6 ± 306.5 | 4,814.1 ± 633.4**# | 4,674.9 ± 615.1** | 4,693.2 ± 617.5** |
  70 mmHg | 6,641.3 ± 849.6 | 2,304.5 ± 695.1 | 4,224.5 ± 944.6** | 4,651.4 ± 823.9** | 4,677.8 ± 563.1** |
  80 mmHg | 6,792.3 ± 893.7 | 2,356.4 ± 310.0 | 4,002.1 ± 526.6** | 4,406.6 ± 579.8** | 4,431.6 ± 583.1** |
1.5 years old | Â | Â | Â | Â | Â |
Female | Â | Â | Â | Â | Â |
  No treatment | 6,664.3 ± 876.8 | 2,777.2 ± 365.4 | 2,661.5 ± 350.2 | 2,550.6 ± 335.6 | 2,444.3 ± 321.6 |
  40 mmHg | 6,672.2 ± 877.9 | 2,780.9 ± 365.9 | 3,398.3 ± 447.1**# | 4,711.4 ± 619.9** | 5,625.3 ± 740.1** |
  50 mmHg | 6,002.8 ± 1,707.0 | 2,803.2 ± 1,397.9 | 4,230.9 ± 594.2**## | 5,104.0 ± 1,121.5** | 6,094.0 ± 931.6** |
  60 mmHg | 6,687.0 ± 879.8 | 2,787.8 ± 366.8 | 4,492.9 ± 591.1**## | 5,208.6 ± 685.3** | 6,307.0 ± 829.8** |
  70 mmHg | 6,619.5 ± 1,166.2 | 2,756.3 ± 954.1 | 4,710.4 ± 827.6**## | 5,295.4 ± 1,312.6** | 6,483.7 ± 1,638.6** |
  80 mmHg | 6,759.1 ± 889.3 | 2,821.5 ± 371.2 | 4,462.5 ± 587.1**## | 5,016.7 ± 660.1** | 6,142.5 ± 808.2** |
Male | Â | Â | Â | Â | Â |
  No treatment | 5,961.5 ± 784.4 | 2,618.5 ± 344.5 | 2,509.4 ± 330.2 | 2,404.9 ± 316.4** | 2,304.7 ± 303.2** |
  40 mmHg | 5,969.8 ± 785.5 | 2,622.0 ± 345.0 | 3,418.3 ± 449.7** | 4,787.5 ± 629.9** | 5,711.2 ± 751.4** |
  50 mmHg | 6,400.8 ± 1,410.1 | 2,654.6 ± 1,154.0 | 4,445.3 ± 761.2** | 5,186.4 ± 1,559.6** | 6,187.1 ± 1,311.6** |
  60 mmHg | 5,985.6 ± 787.5 | 2,628.6 ± 345.8 | 4,719.6 ± 621.0**# | 5,197.9 ± 683.9** | 6,296.6 ± 828.5** |
  70 mmHg | 5,913.7 ± 1,381.5 | 2,598.7 ± 1,130.8 | 4,947.3 ± 1,040.2**# | 5,207.4 ± 781.8** | 6,387.5 ± 1,125.5** |
  80 mmHg | 6,062.6 ± 797.7 | 2,660.5 ± 350.0 | 4,686.9 ± 616.7**# | 4,933.3 ± 649.1** | 6,051.3 ± 796.2** |