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Table 2 Characteristics of patients according to initial rhythm and pre-hospital epinephrine administrationa

From: Effects of prehospital epinephrine during out-of-hospital cardiac arrest with initial non-shockable rhythm: an observational cohort study

Characteristics

Initial shockable rhythm

Initial nonshockable rhythm

 

(N = 15,492)

(N = 194,085)

 

Epinephrine

No epinephrine

Epinephrine

No epinephrine

 

(n = 3,136)

(n = 12,356)

(n = 20,540)

(n = 173,545)

Year

        

2009

1,423

(45.4)

6,410

(51.9)

9,075

(44.2)

84,717

(48.8)

2010

1,713

(54.6)

5,946

(48.1)

11,465

(55.8)

88,828

(51.2)

Mean age (yr)

66.2

(± 15.0)

66.3

(± 15.4)

74.4

(± 15.0)

74.6

(± 16.1)

Male

2,542

(81.1)

9,411

(76.2)

12,344

(60.1)

96,487

(55.6)

Witnessed arrest

2,237

(71.3)

8,581

(69.5)

10,796

(52.6)

53,174

(30.6)

Bystander CPR

1,610

(51.3)

6,323

(51.2)

9,825

(47.8)

77,914

(44.9)

Presumed cardiac cause

2,794

(89.1)

10,743

(87.0)

11,702

(57.0)

93,669

(54.0)

Initial cardiac rhythm

        

Ventricular fibrillation

3,077

(98.1)

12,037

(97.4)

NA

NA

Pulseless ventricular tachycardia

59

(1.9)

319

(2.6)

NA

NA

Pulseless electrical activity

NA

NA

7,460

(36.3)

34,153

(19.7)

Asystole

NA

NA

13,080

(63.7)

139,392

(80.3)

Prehospital actual shock delivery

3,003

(95.8)

11,685

(94.6)

1,719

(8.4)

5,246

(3.0)

Use of advanced airway management

2,035

(64.9)

4,695

(38.0)

15,011

(73.1)

69,151

(39.9)

Call-to-response time, min

7.4

(± 3.3)

7.0

(± 3.2)

8.0

(± 4.1)

7.6

(± 3.8)

Epinephrine administration timeb (min)

15.5

(± 6.9)

NA

17.0

(± 7.8)

NA

Total dose of pre-hospital epinephrine (mg)

      

1

1,213

(38.7)

NA

8,163

(39.7)

NA

2

970

(30.9)

 

6,329

(30.8)

 

≥3

953

(30.4)

 

6,048

(29.4)

 
  1. aCPR, cardiopulmonary resuscitation; EMS, emergency medical services; NA, not available. Values are reported either as n (%) or mean ± standard deviation. Values were missing for 26 to 539 individuals across time variables. bTime from the start of CPR by EMS personnel to the first epinephrine administration.